Pep Guardiola will, therefore, need to make at least one change in attack, although he will also have to factor in Rayan Cherki’s injury, with the summer signing from Lyon now sidelined for two months.
Savinho is yet to feature this term after picking up an injury in pre-season, while Phil Foden was deemed not fully fit to play at Brighton, prior to the international break.
Guardiola also has concerns in defence, as Josko Gvardiol, Rico Lewis and John Stones are all doubts and Abdukodir Khusanov withdrew from Uzbekistan duty with a calf issue.
Manuel Akanji and Ederson left City earlier this month, while Italy goalkeeper Gianluigi Donnarumma arrived, meaning the Blues could have several derby debutants this weekend.