Elsewhere, Magassa’s compatriot Alphonse Areola continues in goal, having been recalled for the Crystal Palace fixture last weekend, behind the same back four of Kyle Walker-Peters, Dinos Mavropanos, Nuno’s former Wolverhampton Wanderers charge Maximilian Kilman and Senegal star El Hadji Malick Diouf.
Lucas Paquetá and Mateus Fernandes play alongside 21-year-old Magassa in midfield.
The wings will be patrolled by Jarrod Bowen and Crysencio Summerville, with Füllkrug up front.
Captain Bowen makes his 199th Premier League appearance for the Club since joining in January 2020. Bowen is also closing in on 250 appearances in all competitions, with this evening’s match being his 245th for the Hammers.
Paquetá is also closing in on a landmark, as tonight’s game marks his 98th Premier League game in West Ham colours since signing from Olympique Lyonnais in summer 2022.
Substitute Wilson will hope to continue his own superb personal form against Everton should he be introduced from the bench. The England striker has scored eight goals in his last seven Premier League games against the Blues, in the form of four braces, one for AFC Bournemouth and three for Newcastle United.
The bench will be filled by goalkeeper Mads Hermansen, Academy of Football trio Ollie Scarles, Freddie Potts and Callum Marshall, defender Igor and midfielders Guido Rodríguez, Andy Irving and Luis Guilherme.
The suspended Tomáš Souček, Ward-Prowse, Aaron Wan-Bissaka, Łukasz Fabiański and George Earthy are not involved.
On the bench, Nuno will be assisted by Mark Robson, Steve Potts, Gerard Prenderville and goalkeeper coach Billy Lepine, all of whom have extensive experience working at the Academy of Football.
Everton: Pickford, O’Brien, Keane, Tarkowski ©, Mykolenko, Gueye, Garner, Dewsbury-Hall, Ndiaye, Grealish, Beto
Subs: Travers (GK), Patterson, Coleman, McNeil, Barry, Dibling, Alcaraz, Aznou, Iroegbunam
West Ham United: Areola, Walker-Peters, Mavropanos, Kilman, Diouf, Magassa, Fernandes, Paquetá, Bowen ©, Summerville, Füllkrug
Subs: Hermansen (GK), Scarles, Igor, Potts, Rodríguez, Irving, Luis Guilherme, Marshall, Wilson
Referee: Sam Barrott