After recovering from a different first hour or so to come back and beat Greece 3-1 on Thursday, Scotland will make changes for what will be a different kind of test.
Lewis Ferguson and Ryan Christie are suspended and Aaron Hickey injured, meaning Billy Gilmour, Lyndon Dykes and Tony Ralston could be in line to start.
Clarke expects Belarus to sit deep at Hampden and make it difficult for Scotland, but said the onus was on his side.
“In my time here, we’ve done well against the so-called lesser teams and it’s very important you get the points off them,” he said.
“They’ll come here and be organised, they’ll be difficult to break down and until you break them down, it’ll be a long night.
“It’s up to us to approach the game properly, which we will. It’s up to us to create enough chances to get the crowd excited, which we hopefully will.”
Clarke also insisted he was not thinking beyond Sunday’s match, with a trip to Greece and a home match against the Danes following next month.
“All I ever try to emphasise is that if you want to qualify, these are the games you have to win,” he said. “If you drop points to the teams ranked below you, it makes qualification difficult.
“No room for complacency. At no point am I looking too far ahead.
“I’ve been in the game a long time and if you look too far ahead, sometimes you trip up – a little bit like [assistant coach] Steven Naismith did in training today when he joined in.”