The programme will conclude a week of Children in Need-related content, including the completion of Sara Cox’s 135-mile challenge.
The Radio 2 presenter is taking part in five marathons in five days, running, jogging and walking through northern England as part of the race.
She’s travelled through Northumberland, Durham, North and West Yorkshire and will end her race at the Salford studio during the show, and will find out how much she has raised for charity.
Big Zuu has also collaborated with Pudsey Bear and a group of children from a theatre project funded by Children in Need to present his first CBeebies Bedtime Story, Basil Dreams Big by Lu Fraser and Sarah Warburton, about resilience, bravery, and believing in yourself.
It was broadcast on Thursday night and is available to stream on BBC iPlayer.
He said the charities that resonate most with him are “ones that take care of carers, and also take care of parents”.
I think youth work projects are very close to me, because I used to be a youth worker.
“I know how crucial it is for young people to have a trusted adult that they can talk to who believes in them and the power this can have in helping unlock their potential,” he said.
Rush, who is hosting for his third year, added that his favourite thing about presenting, along with meeting “so many amazing, inspiring people” was “having the opportunity to hear their stories”.