Twenty eight new jobs have been created to operate the service, which will be delivered by Birmingham Hospice, in partnership with the Birmingham and Solihull Integrated Care Board.
Funding for Spur has come from the Macmillan Cancer Support end-of-life fund.
The hospice also has an existing specialist community palliative care service, which operates from 08:00 to 20:00 GMT, and it is hoped Spur will complement this.
“This service will help patients remain in their preferred place of care and reduce unnecessary hospital admissions by providing wraparound support,” said Paul Bytheway, chief executive at Birmingham Hospice.
“It will reduce the exhaustion and anxiety we know can occur when patients, loved ones and carers don’t know where to turn.”
To access the service from 08:00 to 22:00, contact 0121 809 1900. From 22:00 to 08:00, the dedicated hotline number is 0300 555 1919.