The Scottish government committed to making up to £2.3m available annually for The Thistle, which is overseen by Glasgow City Integration Joint Board.
Scottish drugs minister Maree Todd said the facility had already had a “profound impact”.
“Through the ability of staff to respond quickly in the event of an overdose it has undoubtedly saved lives,” she said.
“I would like to thank all staff and partners for their work in establishing the service, working with some of the most vulnerable people in our society to help save and improve lives, and their continuing efforts to support and engage with the local community.”
Scotland has recorded the highest rate of drug deaths in Europe for the past seven years.
In 2024 there were 1,017 drug misuse deaths, down by 155 on the previous 12 months.
Users of The Thistle are mostly men, with 448 male and 127 female registered in the past year.
Following complaints from neighbours in Calton, in Glasgow’s east end, about an increase in discarded drug paraphernalia, needle bins were installed at “key sites” around the Thistle.
A Glasgow City Council spokeswoman said they now had outreach staff out daily to report back any discarded litter.