Topic joins captain Kenny McLean in midfield, with head coach Liam Manning retaining the shape and 10 of the players who lost 2-0 to Hull at Carrow Road on Saturday.
Tony Springett comes onto the bench in place of Errol Mundle-Smith after he made his debut against the Tigers, with Amankwah Forson and Mathias Kvistgaarden continuing to wait for their first starts since returning from injury.
Liam Gibbs misses out after his latest hamstring injury, with Manning confirming that he’d be absent for between three and four weeks at his pre-match press conference.
Jack Stacey also won’t feature this side of the international break as he recovers from his second concussion of the season, while Ben Chrisene is working his way back from a minor setback to his hamstring.
Lucien Mahovo is in a similar situation, and Jose Cordoba has a thigh problem sustained with Panama during the last international break. Elliot Myles is back in training but not yet ready to feature having been out since pre-season.
Ante Crnac has been ruled out for at least the rest of the current campaign after rupturing his ACL in a 1-0 loss to Derby County last month.
Sheffield Wednesday: Horvath (GK), Fusire, Palmer, Iorfa, M. Lowe, Amass, Valery, Ingelsson, Bannan (C), J. Lowe, Ugbo. SUBS: Stretch, Emery, Otegbayo, Johnson, Alao, Thornton, Fernandes, McNeill, Cadamarteri.
Norwich City: Kovacevic; McConville, Duffy, Darling; Fisher, Topic, McLean (C), Schlupp; Makama, Schwartau, Sargent. SUBS: Grimshaw (GK), Medic, Mattsson, Wright, Springett, Jurasek, Forson, Marcondes, Kvistgaarden.