A police cordon remained in place in Friar Gate until Sunday afternoon, while forensic investigations took place.
Inside the cordon, debris, including shoes and clothing, littered the road and forensic officers in white suits were walking along the street taking pictures.
By Monday morning, the area, which is mostly populated by restaurants and bars, had returned to normal.
Baggy Shanker, MP for Derby South, said he found the incident “deeply shocking”.
“It’s shaken a lot of people,” he said.
“It’s just something we never expect here in Derby.
“My immediate thoughts were around the victims, and all those people that would have seen this and witnessed it, and their families who must have been worried at that time.
“It would have been shocking and scary for everybody involved who were there at that time.”