The Uruguay defender replaces Jeremie Frimpong in the only change from last weekend’s encounter with Nottingham Forest.
Bradley Barcola is included in the squad following his transfer from Paris Saint-Germain and is named on the bench.
Liverpool: Alisson, Van Dijk, Jacquet, Kerkez, Wirtz, Szoboszlai, Isak, Mac Allister, Gakpo, Munoz, Araujo.
Subs: Mamardashvili, Endo, Tsimikas, Barcola, Frimpong, Gravenberch, Nyoni, Koumas, Ngumoha.