With several starting quarterbacks in the NFL battling injury issues, backup quarterbacks played a major role last week and that’s likely to be the case again in Week 4. Carson Wentz was signed just before the season but looked comfortable operating the Minnesota offense in a 48-10 win over Jake Browning and Cincinnati on Sunday. Both backups are set to start again this week with J.J. McCarthy (ankle) and Joe Burrow (toe) out long-term. The Vikings are 2.5-point favorites over the Steelers in Dublin, while the Bengals are 7.5-point underdogs in Denver against the Broncos in one of two Monday Night Football matchups. Elsewhere in the Week 4 NFL odds, the Eagles are 3-point favorites on the road against the Buccaneers, and the Ravens are 2.5-point road favorites over the Chiefs.

Now that the 2025 NFL season is underway, there are plenty of NFL betting opportunities in Week 4, allowing you to scour the NFL odds from the best betting sites and apps. Here’s a closer look at the best sportsbook promos that are available for the Week 4 NFL schedule, including instructions on how to claim each offer.

Where to bet on Week 4 NFL games

The DraftKings promo code, bet365 bonus code, and FanDuel promo code all offer bonus bets after new users place a wager of $5 or more. DraftKings is offering $200 in bonus bets in addition to more than $200 off NFL Sunday Ticket for the upcoming season. The FanDuel’s latest promo code offers new users $300 in bonus bets if their first bet of at least $5 wins.

Both the BetMGM bonus code and Fanatics Sportsbook promo code provide bonus bets, but only if your first bet loses. New users at Fanatics have the ability to get $100 in FanCash along with 20+ $100 No Sweat Bets in FanCash if your first football bet loses on every Game Day until October. Meanwhile, the BetMGM bonus code CBSSPORTS awards new users up to $1,500 back in bonus bets if their first bet loses. BetMGM users in New Jersey, West Virginia, Pennsylvania or Michigan can get a different promotion and receive $150 in bonus bets if you win your first bet of $10 or more. 

The Caesars Sportsbook promo code is completely different than the others, offering profit boosts instead of bonus bets. After placing a wager of $1 or more, you receive 20 100% profit boost tokens.

Bettors can use any of these promotions for any game on the Week 4 NFL schedule.

Week 4 NFL betting preview, picks

Washington Commanders (-2.5) vs. Atlanta Falcons | 1 p.m. ET | Sunday, Sept. 28

Marcus Mariota stepped in with Jayden Daniels (knee) sidelined last week, and Washington still managed a convincing 41-24 win over Las Vegas. Mariota threw for 207 yards on 15-of-21 passing with a touchdown and also ran six times for 40 yards and another score. The Commanders rushed for over 200 yards as a team, and that will likely continue to be their identity if Daniels is held out again. Meanwhile, the Falcons are coming off an embarrassing 30-0 loss to the Panthers, where Michael Penix Jr. went 18-for-36 with two interceptions. The model is projecting that Washington covers in 65% of simulations.

Over 44.5 points: Tampa Bay Buccaneers vs. Philadelphia Eagles | 1 p.m. ET | Sunday, Sept. 28

The Eagles needed a stunning comeback to sneak past the Rams and get to 3-0 last week. Now, they’ll head to Tampa Bay to take on the 3-0 Buccaneers as they come back from nearly squandering a large fourth-quarter lead to the Jets. Both teams have shown the ability to grind out tough wins early in the season, and these look like two of the better teams in the NFC. This could turn into a possession-by-possession battle, and the model projects the over hits in 57% of simulations.

Chicago Bears (+1.5) vs. Las Vegas Raiders | 4:25 p.m. ET | Sunday, Sept. 28

It took a few weeks for Caleb Williams and Ben Johnson to start to gel, but everything seemingly clicked during a 31-14 win over the Cowboys at Soldier Field last week. Williams went 19-of-28 for 298 yards and four touchdowns, and the Chicago offense is suddenly top 10 in both scoring and total yardage. Meanwhile, the Raiders have suffered back-to-back losses by double-digits to the Chargers and Commanders, with the defense giving up 41 points last week to a backup QB. The model predicts that the Bears cover in 58% of simulations.

Responsible gaming

Practicing responsible gaming is paramount, which is why all the top sportsbooks have tools and resources available on their apps and websites, including time and wager limits, voluntary self-exclusion options, and more. Several are equipped with live 24/7 chat support, and all offer links and phone numbers for local and national problem gambling helplines. If you or someone you know is dealing with a gambling problem, please reach out to trained professionals such as the Problem Gambling Help Network at 1-800-GAMBLER.