Developing a successful NFL DFS strategy can take many forms, but one of the most common approaches is focusing on games with the highest projected point totals when identifying top NFL DFS picks and building NFL DFS stacks. The highest over/under in the Week 8 NFL odds for the Sunday main slate is 51 in the Cowboys vs. Broncos matchup. Other potential high-scoring matchups include Bears vs. Ravens (49.5), Titans vs. Colts (47.5), and Buccaneers vs. Saints (46.5). Thus, you can expect stars like Dak Prescott, Bo Nix, CeeDee Lamb, Derrick Henry and Jonathan Taylor to be core players in many NFL DFS lineups. 

Players of that caliber, however, will set back your NFL DFS salary cap, forcing you to search for more potential NFL DFS sleepers and NFL DFS values. Should players like Daniel Jones or Baker Mayfield find their way into your quarterback slot for Sunday’s main slate? Will underperforming players like Saquon Barkley and Tua Tagovailoa finally live up to their price tags on NFL DFS sites? Before making any NFL DFS picks for Sunday or locking in NFL DFS lineups on sites like DraftKings and FanDuel, be sure to check out SportsLine’s advanced NFL DFS lineup optimizer.

New users can also target the latest Underdog promo code, where they can pick at Underdog and get $100 in site credits after making a $5 wager:

The DFS Optimizer uses info from the SportsLine Advanced-Data Projection Model and DFS Professional Millionaire Mike McClure to identify top DFS picks/plays for any slate on betting apps like DraftKings and FanDuel. It simulates every game 10,000 times to help DFS players optimize and build winning DraftKings and FanDuel lineups. Optimize, export, and enter lineups confidently with injury updates, floor and ceiling player projections, and Vegas lines and picks all with one winning tool for sports betting apps.

Now, SportsLine’s NFL DFS Optimizer has turned its attention to Sunday’s 2025 NFL Week 8 schedule and just locked in its top daily Fantasy football lineups. You can only see its optimal lineups at SportsLine.

New users can get $50 in Pick6 credits at DraftKings when they play $5.

Top NFL Week 8 DFS picks for Sunday

One of the optimizer’s top DFS value picks for Sunday is Colts quarterback Daniel Jones ($6,100 on DraftKings and $7,700 on FanDuel). The former first-round pick out of Duke signed with the Indianapolis Colts in 2025 after a challenging 2024 season with the New York Giants. In 2024, he played in ten games and threw for 2,070 yards with eight touchdowns and seven interceptions, completing 63.3% of his passes with a 79.4 passer rating. 

Jones beat out Anthony Richardson for the Colts’ starting job, and has gotten off to an outstanding start to the 2025 season. He’s thrown for 1,790 passing yards, ten touchdowns, and just three interceptions through seven games, with a passer rating above 105 and 83 yards and four scores on the ground. Jones is averaging roughly 255 passing yards per game this season and has elevated the Colts’ offense into one of the more efficient units in the AFC. See who else to pick here.

The optimizer’s NFL DFS strategy also includes rostering Broncos wide receiver Courtland Sutton ($6,200 on DraftKings and $7,700 on FanDuel). The former second-round pick out of SMU had a strong 2024 campaign with the Broncos, catching 81 passes for 1,081 yards and eight touchdowns while averaging 13.3 yards per reception. Entering the 2025 season, he’s off to another solid start. 

Through seven games, Sutton has 33 receptions for 469 yards and three touchdowns with a 14.2-yard per catch average. Sutton’s consistency and chemistry with quarterback Bo Nix have helped stabilize Denver’s passing game, particularly in key third-down and red-zone situations. At 6-foot-4, Sutton remains one of the league’s most reliable contested-catch receivers, using his size and strength to win battles downfield. You can see the rest of the optimizer’s NFL DFS picks here.

New users can also check out the latest FanDuel promo code and get $300 in bonus bets instantly at FanDuel if your $5 bet wins. 

How to build Sunday Week 8 NFL DFS lineups

The NFL DFS Optimizer is also targeting multiple undervalued players who could explode for huge numbers on Sunday. Those players could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who they are, and the rest of the optimizer’s NFL DFS picks, at SportsLine. 

So what is the optimal NFL DFS lineup for Sunday, and which under-the-radar NFL DFS picks offer huge value? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice and stacks, all from an NFL DFS optimizer that simulates every game 10,000 times, and find out.