Welterweight champion Jack Della Maddalena takes on former lightweight king Islam Makhachev in the main event of UFC 322 on Saturday night. The main card is set for 10 p.m. Et from Madison Square Garden.

Makhachev is a -270 favorite (risk $270 to win $100), while Della Maddalena is priced at +220 (risk $100 to win $220) in the latest MMA odds for UFC 322: Della Maddalena vs. Makhachev. 

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Before making any UFC 322 picks, make sure you see the MMA predictions and betting advice from SportsLine expert Daniel Vithlani. 

Vithlani is a highly analytical UFC bettor who has been a consistent winner for SportsLine members since making his debut in January 2023 with a 5-0 record for UFC 283. In fact, he’s up over $1,500 on his UFC main card picks!

His other highlights include calling an upset for Sean O’Malley (+210) against Aljamain Sterling (-250) at UFC 292 as part of a 4-1 main card, and his UFC 299 winners included underdog selections on Dustin Poirier (+190) against Benoit Saint Denis (-230) and Michael Page (+110) against Kevin Holland (-130). Anyone who has followed him could be way up.

This week at UFC 322: Della Maddalena vs. Makhachev, Vithlani is backing  Malcolm Wellmaker (-165) to get past Cody Haddon (+140) in a bantamweight matchup on the preliminary card. 

He’s also backing a fighter whose “constant barrage of strikes and takedowns” will lead to a MASSIVE victory! You ABSOLUTELY need to see his UFC Fight Night picks before making any of your own!

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