Down Syndrome has been one of the leading conditions in the world. It is a genetic disorder that leads to developmental delays including heart issues, hearing disability, learning and speech impairment. But as per recent studies, in a groundbreaking research Japanese scientists have been working on how to alter chromosomes that can help remove the ones associated with Down Syndrome. Â
Japan the futuristic country of the world may have found a way to cure Down syndrome
Down syndrome is caused by the presence of an extra copy of chromosome 21. This usually impacts the brain development, the body can produce too much of proteins and physical changes like heart defects, weakened immune system and other conditions show up. Scientists have been long into the research on how to remove this copy, which can be the ultimate cure for it. Editing the genes showed that genes that help develop the brain became more active, while those linked to metabolism slowed down.
While still in the early stages, Japanese scientists are optimistic that their research could lead to significant breakthroughs shortly. Through the help of CRISPR-Cas9, a significant gene-editing system, scientists are exploring ways to delete the effects of the extra chromosome 21, essentially aiming to correct the genetic imbalance at the cellular level.
To expand the scope of their findings, researchers tested the technique not only on lab-grown stem cells but also on skin fibroblasts, more mature cells taken from individuals with Down syndrome. Remarkably, even in these fully developed cells, the experiment showed promising results, suggesting broader potential for future applications.
This groundbreaking research is still in its very early stages, so it won’t lead to immediate treatments or applications. However, it offers hope for a better future for those living with Down syndrome. The process itself is fascinating, scientists are learning how to edit genes, showcasing the incredible progress of modern science and its potential to transform lives.
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