Abdullah Fazal, Amad Butt, Azan Awais and Ghazi Ghori have all earned call-ups for the two-match Test series, starting on 8 May.
Fazal and Awais, both left-handed batters, have been rewarded for their strong domestic performances. Butt, a bowling all-rounder, has over a decade of experience in domestic cricket, having made his first-class debut in 2015.
Wicketkeeper batter Ghori, meanwhile, already has international exposure in white-ball cricket, having made his ODI debut against Bangladesh last month.
The squad also includes experienced campaigners in Babar Azam, Mohammad Rizwan, Shaheen Afridi, Noman Ali, Sajid Khan and Salman Ali Agha, among others.
Squad: Shan Masood (captain), Abdullah Fazal, Amad Butt, Azan Awais, Babar Azam, Hasan Ali, Imam-ul-Haq, Khurram Shahzad, Mohammad Abbas, Mohammad Rizwan, Ghazi Ghori, Noman Ali, Sajid Khan, Salman Ali Agha, Saud Shakeel and Shaheen Shah Afridi