Fears are rapidly growing for a 26-year-old Melbourne woman who failed to board her flight home from the US five days ago.

Sally Grace Contarino was reported missing by her concerned loved ones after she failed to return home as scheduled on June 21.

Ms Contarino’s family confirmed to the Herald Sun that she was travelling alone and was last seen in the Mount Charleston area of Nevada.

They have not heard from the Lyndhurst woman since June 20, one day before she was expected to land, and are now seeking information regarding her wellbeing and location.

The last photo she shared from her trip was from the small, mountainous town of Mount Charleston, 60km east of Las Vegas.

Ms Contarino is described as being of slim build with fair skin, brown hair and brown eyes.

The Las Vegas Metropolitan Police Department has opened a missing persons case seeking the public’s assistance in finding Ms Contarino.

Local hospitals have been put on alert and were urged to check their records in case she was admitted.

Victoria Police was not aware of her disappearance, and the Department of Foreign Affairs and Trade was contacted for comment.

Anyone with information is urged to contact the Las Vegas Police Department on www.lvmpd.com/contact/contact-us.