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It’s looking like Lamar Jackson will miss a second straight game for the Baltimore Ravens as the quarterback deals with a hamstring injury.

Jackson missed his sixth straight practice on Friday and the two-time NFL MVP is likely to miss their Week 6 matchup against the Los Angeles Rams. The Ravens have their bye in Week 7, which would give Jackson an extra week of recovery time in hopes that he could return for the Oct. 26 game against the Chicago Bears.

Should Jackson be ruled out, Cooper Rush will step in again. He went 14-for-20 for 179 yards, zero touchdowns and three interceptions last week during a 44-10 loss to the Houston Texans, which dropped Baltimore to 1-4 on the season.

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Another regular starting quarterback who could sit out Week 6 is Brock Purdy of the San Francisco 49ers.

A toe injury has kept Purdy off the field, opening the door for Mac Jones to step in for another week after leading the 49ers to three wins in his three starts. Jones, however, was limited in practice on Thursday as he works through left knee and oblique injuries.

“[I’m] just getting treatment every day and working,” Jones said, via ESPN. “I feel confident and just working through it day by day. That’s all you can do.”

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Other notable Week 6 injuries:

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The Tampa Bay Buccaneers trio of running back Bucky Irving and wide receivers Mike Evans and Chris Godwin have been ruled out. Irving has been bothered by foot and shoulder injuries, while Evans has been suffering with a bad hamstring and Godwin has a fibula injury that is in a different location than the ankle injury he suffered last season. He is considered week-to-week and isn’t expected to land on injured reserve.

Kyler Murray was back at practice on Friday after sitting out the past two days with a foot injury. Arizona Cardinals head coach Jonathan Gannon had labeled the quarterback “day-to-day” with Jacoby Brissett ready should Murray not end up playing.

As Noah Brown returned to practice, a quad injury has kept Washington Commanders wide receiver Terry McLaurin from the field this week, but head coach Dan Quinn expressed confidence he’ll be available Monday night against the Chicago Bears.

Tee Higgins and Andrei Iosivas could be Joe Flacco’s main receiving targets after the Cincinnati Bengals announced that Ja’Marr Chase is listed as questionable with an illness. Head coach Zac Taylor said the All-Pro receiver began feeling under the weather on Thursday night.

Week 6 byes: Houston Texans, Minnesota Vikings

Here’s the rest of the Week 6 injury report:

DENVER BRONCOS

OLB Jonah Elliss (ribs, shoulder): OUT

G Ben Powers (biceps): OUT

DL Malcolm Roach (calf): questionable

NEW YORK JETS

CB Michael Carter II (concussion): OUT

WR Allen Lazard (not injury related): OUT

CB Brandon Stephens (neck): questionable

LB Ja’Markis Weston (groin): questionable

LOS ANGELES RAMS

RT Rob Havenstein (ankle): doubtful

WR Tutu Atwell (hamstring): questionable

BALTIMORE RAVENSSEATTLE SEAHAWKSJACKSONVILLE JAGUARS

TE Brenton Strange (hip): OUT

DALLAS COWBOYSCAROLINA PANTHERS

RB Chuba Hubbard (calf): OUT

OT Taylor Moton (elbow): OUT

DT Tershawn Wharton (toe): OUT

CB Akayleb Evans (hamstring): OUT

WR Jalen Coker (quad): questionable

TE Ja’Tavion Sanders (ankle): questionable

CB Mike Jackson (ribs): questionable

CB Chau Smith-Wade (chest): questionable

CLEVELAND BROWNSPITTSBURGH STEELERSNEW ENGLAND PATRIOTS

RB Antonio Gibson (ACL): OUT

OLB Keion White (elbow): OUT

S Jaylinn Hawkins (hamstring): OUT

OLB Anfernee Jennings (ankle): OUT

CB Christian Gonzalez (hamstring): questionable

NEW ORLEANS SAINTSLOS ANGELES CHARGERS

RB Omarion Hampton (ankle): OUT

WR Derius Davis (knee): OUT

RT Trey Pipkins (knee): OUT

DT Da’Shawn Hand (groin): OUT

FB Scott Matlock (ankle): questionable

WR Quentin Johnston (hamstring): questionable

RG Jamaree Salyer (knee): questionable

OLB Bud Dupree (hamstring): questionable

LB Denzel Perryman (ankle): questionable

MIAMI DOLPHINS

LB Tyrel Dodson (concussion): OUT

S Elijah Campbell (quad): OUT

CB Storm Duck (ankle): questionable

ARIZONA CARDINALSINDIANAPOLIS COLTS

RB Tyler Goodson (groin): OUT

CB Kenny Moore (Achilles): OUT

TENNESSEE TITANS

WR Bryce Oliver (knee): OUT

RG Blake Hance (shoulder): OUT

OLB Arden Key (quad): OUT

CB Marcus Harris (calf): OUT

K Joey Slye (right calf): OUT

LAS VEGAS RAIDERSSAN FRANCISCO 49ERSTAMPA BAY BUCCANEERS

RB Bucky Irving (foot, shoulder): OUT

WR Mike Evans (hamstring): OUT

WR Chris Godwin (fibula): OUT

CINCINNATI BENGALS

DE Shemar Stewart (ankle): doubtful

WR Ja’Marr Chase (illness): questionable

LG Dylan Fairchild (knee): questionable

C Matt Lee (knee): questionable

RG Lucas Patrick (calf): questionable

GREEN BAY PACKERS

WR Christian Watson (knee): OUT

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