Your Week 11 NFL betting guide would be smart observe the trends, regardless if you want to follow them with Week 11 NFL predictions. The Browns are the only team undefeated ATS at home, and they are 8-point home underdogs to the Ravens, per the latest NFL odds. Meanwhile, the Seahawks are 4-0 ATS on the road as they’ll visit the Rams (-3) on Sunday. So, should you back the Browns or Seahawks with Week 11 NFL bets or as a part of an NFL parlay?

The aforementioned are two of the nine divisional matchups this week, with others including Panthers vs. Falcons (-3.5), Bears vs. Vikings (-3), and Chiefs vs. Broncos (+3.5). The likes of Bijan Robinson, Justin Jefferson, Patrick Mahomes and Travis Kelce have had lots of success versus their rivals, so should your Week 11 NFL picks include any of them as part of your NFL DFS strategy, within Fantasy football lineups or among NFL player props? If you are looking for NFL picks, NFL parlays, Fantasy football rankings or NFL DFS picks for Week 11, SportsLine has you covered with its proven model, Machine Learning Model and team of experts. Join SportsLine here, and for a limited time get your first month for $1 using promo code CHAMPIONSHIP. 

NFL parlay picks could generate massive payouts

SportsLine’s model has returned well over $7,000 on top-rated NFL betting picks since its inception, so those picks can confidently be used to fill out NFL parlay picks on betting apps. The model has built a five-team parlay for Week 11 that pays 25-1, and one of the legs is the Cowboys (-3.5, 50.5) covering against the Raiders on Monday. The model has Dallas covering in 60% of simulations, and the rest of the five-team parlay can be found here.

You can also bet this parlay at DraftKings, where you can get $300 in bonus bets + 3 months of NBA League Pass if your initial $5 wager wins. 

NFL DFS picks from top experts 

SportsLine has a DFS Optimizer that simulates every game 10,000 times and uses info from the SportsLine Projection Model and DFS Professional Millionaire Mike McClure to identify top DFS picks/plays for any slate on sites like FanDuel and DraftKings. It has the Jags’ Travis Etienne as one of its top value picks at running back, while Tampa’s Cade Otton is among the best values at tight end for Sunday’s main slate. Here are its complete Week 11 NFL DFS rankings. 

Senior Fantasy Writer Heath Cummings has locked in his projections for every Fantasy relevant quarterback, running back, wide receiver and tight end. Not only do you get statistical projections as well as Fantasy point totals for every player in different scoring formats, but Cummings also includes DFS prices and values to help build winning DFS lineups each week. He has the Cardinals’ Jacoby Brissett as a top-10 Fantasy quarterback this week. Get his full Week 11 Fantasy and DFS projections right here. 

New users can also make picks at Underdog and get $100 in site credits after making a $5 wager:

Fantasy rankings to help you win your matchups

SportsLine’s model simulates every game 10,000 times, which has helped it produce better Fantasy rankings than human experts over the last few seasons. It has revealed its Week 11 Fantasy football rankings that can be used to make start-sit decisions. The Steelers’ Aaron Rodgers is projected to be a top-12 Fantasy quarterback this week, and the model also has full rankings for every position right here. 

Advanced NFL model simulates every game 10,000 times 

SportsLine’s model enters Week 11 of the 2025 NFL season up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 11 on a 47-32 run on top-rated picks dating back to 2024 and has revealed picks for every Week 11 NFL game. One of its favorite picks is the Bears (+2.5, 48.5) covering versus Minnesota, which cashes over 50% of the time. You can find the model’s picks for every NFL Week 11 game here. 

You can also use the latest FanDuel promo code to get $150 in bonus bets instantly:

NFL Vegas expert picks revealed 

SportsLine has an expansive team of NFL experts who provide quality betting advice for every game on the schedule. Jeff Hochman, who is 5-1 (+485) over his last six picks in Ravens games is backing Cleveland (+8.5) to cover at home versus Baltimore. “Cleveland has a point differential of -15.3 in unfamiliar territory, while at home, they post a +9.0 point differential in the Dawg Pound. The Ravens crushed the Browns 41-17 as 12.5-point home chalk despite getting outgained 322-242 back in Week 2 with Joe Flacco under center… Myles Garrett called out his team after last week’s loss, and the Browns will be highly motivated in this division matchup. With 15-25 mph winds and a 50% chance of light rain, we have the makings of a closer-than-expected low-scoring contest.” Hochman’s NFL best bets for Week 11 can be found here.

Jets vs. Patriots ‘Thursday Night Football’ picks

The Patriots, riding a seven-game win streak, will host the Jets, who’ve won back-to-back contests, in a divisional matchup on ‘Thursday Night Football’. New England is a 13-point favorite, in a game with the largest of the Week 11 NFL spreads. The total is 43.5, and the advanced SportsLine model has the Over hitting in over 70% of simulations in an A-rated pick. NFL expert Emory Hunt, who is 18-9 (+805) over his last 27 ATS picks in Jets games, is backing New England to cover. Of the Jets, Hunt says, “Unless they find a way to balance out the offense and not rely solely on their run game to bail them out, this team will struggle to find points against anyone they face.” See Hunt’s full analysis for ‘Thursday Night Football’ at SportsLine.