Williams also injured his hamstring in the game, playing just the first snap of the game. Williams’ status could be the most worrisome as he did not practice this week.

Kittle was absent from the Bears’ win after sustaining a low ankle sprain in Week 16. He’s been adamant this week that he’ll play. The seven-time Pro Bowler has 52 catches for 599 yards and seven touchdowns in 10 starts this season, having missed six games due to injury. Perhaps most importantly, the 49ers are 8-2 with him in the lineup this season. Kittle participated in all three of the team’s practices this week in a limited capacity.

Pearsall played Sunday, but has dealt with injuries all season, having missed seven games. He’s recorded 36 receptions for 528 yards and no touchdowns. Like Kittle, Pearsall’s been limited in each practice.

The 49ers (12-4) kick off against the visiting Seahawks (13-3) at 8 p.m. ET Saturday.