Tszyu has had a frustrating year, with a recurring hand injury delaying his comeback.
He had surgery on it late last year, and reinjured it in sparring earlier in 2025.
It’s one of the biggest talking points ahead of his comeback tonight, with Tszyu hoping he gets through unscathed.
In the co-main event, Michael Zerafa fights American Mikey Dahlman.
There’s been plenty of talk around Zerafa’s absence from Monday’s press conference, but he’ll be good to go tonight.
If they both win, Tszyu and Zerafa are scheduled to meet in a domestic blockbuster in December.
Meanwhile, Sydney fighter Brock Jarvis is also on the card, taking on Sam Beck.
If a fight between Tszyu and Zerafa falls apart, Jarvis – who is back training with Jeff Fenech – will step in to fight ‘The Butcher’.
The fight of the night is down the card though, with rising Sydney star Ahmad Reda stepping up for the biggest bout of his career against veteran Bruno Tarimo.
They’re two of the most avoided fighters in the country, and the Australian super-lightweight title will be on the line.
WHAT TIME DOES TSZYU-ISMAILI START?
Doors open at 5pm and the first prelim fight is at 5:30pm.
The PPV card gets underway at 7pm.
WHAT TIME IS NIKITA TSZYU FIGHTING?
Expect Nikita Tszyu to fight at around 10-10:30.
HOW TO WATCH NIKITA TSZYU’S FIGHT
You can watch the fight on Kayo Sports or Main Event PPV.
TSZYU VS ISMAILI FULL UNDERCARD
PPV Card
Nikita Tszyu vs Lulzim Ismaili – 10 rounds – super-welterweight
Michael Zerafa vs Mikey Dahlman – 10 rounds – middleweight
Brock Jarvis vs Sam Beck – 8 rounds – middleweight
Ahmad Reda vs Bruno Tarimo – 10 rounds – super-lightweight
Jasmine Parr vs Afasha Kamarudin – 5 rounds – super-flyweight
Prelims
Jacob Clenshaw vs Isaias Sette – 5 rounds – featherweight
Ash Heal vs Shannon Rose – 4 rounds – super-middleweight
Brandon Grach vs Lesio Balekasavu – 4 rounds – heavyweight
Blair Geraghty vs Saimoni Nanovu – 4 rounds – super-lightweight