Strong Fantasy football teams capable of winning a championship need to have strong running back and wide receiver positional groups, as well as solid quarterback and tight end play. It is imperative to have solid opening rounds of your 2025 Fantasy football drafts in order to build a championship-caliber roster. Kickers and defense are important, but it’s necessary to solidify your other areas first. Because the wide receiver group has more players to choose from overall, targeting a running back first could be a sound Fantasy football draft strategy.

DeAndre Hopkins was an example of just how deep the wide receiver depth was in 2024. He ranked 50th in positional Fantasy points but outscored a number of top-40 Fantasy running backs and tight ends. To experience success, you need to have the most up-to-date 2025 Fantasy football advice you can get. Before crafting your 2025 Fantasy football draft strategy, be sure to check out the 2025 Fantasy football positional rankings and cheat sheets from the proven computer model at SportsLine.

Last year, the model accurately predicted that Dolphins running back Raheem Mostert’s disappointing follow-up to a breakout 2023 season. It also called C.J. Stroud’s down year, predicted Jayden Daniels’ breakout campaign and projected James Cook to become one of Fantasy football’s elite running backs in 2024.

The same model has a proven track record providing Fantasy football tips, identifying A.J. Brown as a sleeper in 2020, nailing Jonathan Taylor’s monstrous season in 2021 and correctly predicting C.J. Stroud would take a step back in 2024. Additionally, it’s called past Fantasy football sleepers like Derrick Henry in 2019, Christian McCaffrey and Alvin Kamara in 2018 and Davante Adams in 2017. 

Now, SportsLine has simulated the entire NFL season 10,000 times and released its latest Fantasy football positional rankings 2025, along with plenty of sleepers, breakouts and busts at every position. Head to SportsLine now to see them. 

Top 2025 Fantasy football QB rankings

Here’s a look at SportsLine’s top 2025 Fantasy football QB picks: 

1. Lamar Jackson, Baltimore Ravens: Jackson had a career year in 2024, throwing for 4,172 yards and 41 touchdowns while averaging an impressive 8.8 yards per attempt and posting a 119.3 QB rating. On the ground, he added 915 rushing yards and four rushing touchdowns. His exceptional dual-threat abilities led him to finish more than 50 points ahead of any other quarterback in CBS Sports PPR leagues. Jackson’s continued development as a passer combined with his elite running skill firmly establishes him as the top fantasy QB entering 2025.

2. Josh Allen, Buffalo Bills: Though Jackson posted flashier stats, Allen earned the 2024 NFL MVP honors with 40 total touchdowns and over 4,000 yards of offense. He has ranked as a top-two fantasy quarterback for five consecutive seasons, proving his consistent value. Allen’s arm talent ranks among the best in NFL history, and his running ability often goes underappreciated.

3. Joe Burrow, Cincinnati Bengals: Burrow dominated the league last season, leading in completions (450), attempts (652), passing yards (4,918), and touchdowns (43). His chemistry with a strong receiving corps — Ja’Marr Chase, Tee Higgins, Chase Brown, and Mike Gesicki — sets the stage for another prolific season. Burrow remains a high-volume, high-scoring fantasy option heading into 2025. See more top QBs here.

Top 2025 Fantasy football RB rankings

Here’s a look at SportsLine’s top 2025 Fantasy football RB picks:

1. Bijan Robinson, Atlanta Falcons: Robinson just keeps getting better after being selected eighth overall in the 2023 NFL Draft by the Falcons. After just missing out on a 1,000-yard rushing season his first year, he came on strong in 2024. In 17 games last year, he carried 304 times for 1,456 yards and 14 touchdowns. He also caught 61 passes for 431 yards and one touchdown.

2. Saquon Barkley, Philadelphia Eagles: The 28-year-old was rejuvenated when he signed as a free agent last season. In 16 games, he carried 345 times for 2,005 yards and 13 touchdowns. He also caught 33 passes for 278 yards and two more scores. In seven seasons, including his first six with the New York Giants, he has played in 90 regular-season games, rushing for 7,216 yards and 48 touchdowns.

3. Jahmyr Gibbs, Detroit Lions: The 23-year-old enters his third season in the league. He was the 12th pick of the first round in the 2023 NFL Draft by the Lions. He had a breakout season last year, rushing 250 times for 1,412 yards and 16 touchdowns in 17 games. He also caught 52 passes for 517 yards and four touchdowns. See more top RBs here.

Top 2025 Fantasy football WR rankings

Here’s a look at SportsLine’s top 2025 Fantasy football WR picks: 

1. Ja’Marr Chase, Cincinnati Bengals: Chase has eclipsed 1,000 receiving yards in each of his first four seasons in the NFL. He set career highs across the board in 2024, totaling 127 receptions for 1,708 yards and 17 touchdowns. He finished WR1 last season and is on track for repeat success in 2025.

2. Justin Jefferson, Minnesota Vikings: Jefferson has finished in the top five in fantasy points per game in each of his last four seasons. He is also coming off of a bounce-back 2024 season where he tallied 103 receptions for 1,533 yards and 10 receiving touchdowns. If J.J. McCarthy has a breakout season, Jefferson could be looking at another strong fantasy campaign.

3. Brian Thomas Jr., Jacksonville Jaguars: Thomas had a sleeper rookie campaign, giving fantasy managers 16.7 fantasy points per game in 2024. He finished third in the NFL with 1,282 receiving yards and tied for sixth with 10 receiving touchdowns. New head coach Liam Coen was offensive coordinator in Tampa Bay last season, and he could unlock Jacksonville’s air game even more this season. See more top WRs here.

Top 2025 Fantasy football TE rankings

Here’s a look at SportsLine’s top 2025 Fantasy football TE picks:

1. George Kittle, San Francisco 49ers: In 2024, Kittle had his best season for Fantasy managers since 2018, averaging 15.8 PPR points per game. Kittle has scored at least seven touchdowns in each of his past four seasons, and he saw his targets spike to 6.3 per game a season ago. The veteran tight end is coming off back-to-back 1,000-yard seasons, a big reason why SportsLine’s model ranks him as the No. 1 TE heading into 2025. 

2. Brock Bowers, Las Vegas Raiders: As a rookie, Bowers averaged nine targets per game. That high volume helped Bowers average 15.5 PPR points per game. He ended his incredible 2024 campaign with the most receptions by a rookie in NFL history (112) and the most yardage (1,194) by a rookie tight end in league history. Geno Smith marks a significant upgrade at quarterback in Las Vegas, so there’s no ceiling to what Bowers can do in 2025.

3. Trey McBride, Arizona Cardinals: McBride has cemented his status as a top-tier Fantasy tight end after a breakout 2024. McBride averaged 9.2 targets per game to lead all tight ends, catching 76% of his targets. He has only seven career touchdowns in 49 games, but SportsLine’s model expects he’ll be a differentiator at tight end to give your Fantasy squad an advantage every week. See more top TEs here.

Top 2025 Fantasy football defense rankings 

Here’s a look at SportsLine’s top three 2025 Fantasy football D/ST picks:

1. Philadelphia Eagles D/ST: Howie Roseman is one of the NFL’s best executives but his turnaround of the Philadelphia pass defense from 2023 to 2024 was masterful. They went from ranking 30th in points allowed and 26th in yards allowed to ranking second in scoring defense and first in total defense in just one offseason. Now most of the key pieces from that unit return.

2. Baltimore Ravens D/ST: Baltimore had the best run defense in football last season and should have an improved secondary after drafting Malaki Starks in the first round and signing Jaire Alexander. They’ve got high-level playmakers at every level in Kyle Van Noy, Roquan Smith and Kyle Hamilton.

3. Minnesota Vikings D/ST: They were the No. 5 scoring defense in the NFL last season and they led the NFL with 33 takeaways. Minnesota also scored three defensive touchdowns, and even if the takeaway numbers can’t be relied on, the boom potential here is too high to ignore. See more top D/ST here. 

Top 2025 Fantasy football kicker rankings

Here’s a look at SportsLine’s top 2025 Fantasy football K picks: 

1. Brandon Aubrey, Dallas Cowboys: Aubrey has the biggest leg in the league and he tied for second in the NFL in points (150) last season. He’s 76-of-85 on field goals the last two seasons and he’s a staggering 24-of-27 from 50 yards or more.

2. Matt Gay, Washington Commanders: Jayden Daniels is the rising tide that lifts all boats and this offense looks primed to be even better in 2025 after the offseason additions of Laremy Tunsil and Deebo Samuel. Gay was perfect from inside of 50 yards last season and closed the year strong, with 24 points in the final two games of the regular season.

3. Tyler Bass, Buffalo Bills: Despite only making 82.8% of his field goal attempts, Bass finished tied for ninth in scoring (131 points). He was perfect on field goals of more than 50 yards and also locked in during the 2025 NFL playoffs, going 6-for-6 overall.

How to find proven 2025 Fantasy football rankings

SportsLine has ranked almost every Fantasy-relevant player at every position and you can see their entire 2025 Fantasy football positional rankings now. You can only see their top sleepers, breakouts and busts at every position at SportsLine.

So who are the top players at every position and who is being underrated? Visit SportsLine now to get 2025 Fantasy Football cheat sheets for every single position, all from the model that regularly outperforms human rankings.