Scientists reveals how cancer-causing p53 mutations remain invisible to the immune system
One of the biggest challenges in cancer immunotherapy may not be that immune cells are too weak, but…
Gut infection leaves long-lasting immune ‘memories’ at the brain’s borders in mice
A mouse study traces how immune cells activated in the intestine migrate to the dura and persist at…
Could scorpion venom inspire new treatments for liver disease?
From blocking inflammatory immune pathways to disrupting hepatitis viruses, scorpion-derived peptides are attracting attention as potential drug candidates,…
Glioma microenvironment emerges as key target for future therapies
The prognosis for glioma patients remains extremely poor despite aggressive multimodal standard therapy: maximal safe resection, radiotherapy, and…
New strip test provides rapid screening for canine Lyme disease
Announcing a new article publication for Zoonoses journal. This study was aimed at developing and preliminarily validating a…
Wistar scientists develop new bispecific T cell engager to target ovarian cancer
Wistar scientists have developed a new type of bispecific T cell engager, or BTE, that is effective against…
Memory B cells reveal how nasal vaccines could stop respiratory infections earlier
New insights into lung-resident memory B cells show why the next generation of vaccines may need to protect…
New breast cancer classification system predicts immunotherapy response success
The advent of immune checkpoint inhibitors (ICIs) has marked a paradigm shift in cancer treatment, yet a significant…
Cytokine-armored CAR-T cell therapy successfully attacks aggressive brain tumors in mice
Scientists at the UCLA Health Jonsson Comprehensive Cancer Center have developed a new cytokine-armored CAR-T cell therapy that helps the…
Turning the flu virus Into a powerful tool to fight cancer
A recent Views & Comments article published in Engineering highlights advances in repurposing influenza viruses as flexible therapeutic…
Innovative light probes allow real-time visualization of cellular processes
Fluorescent proteins have revolutionized science, enabling researchers to tag and visualize individual molecules in living cells, tissues, and…
Targeting glutamine metabolism enhances CAR-macrophage cancer therapy
Tumor-associated macrophages (TAMs) within the tumor microenvironment (TME) exhibit significant metabolic dysregulation, which impairs their antitumor function. Specifically,…