Bacterial enzyme linked to heart complications in pneumonia
Pneumonia is a disease that burdens the healthcare system with more that 1.2 million emergency room visits each…
X-LDR: an atlas of linkage disequilibrium across species | Genome Biology
Overview of the studyDatasets The study surveyed human and nonhuman samples (Table 1). Human samples included 1KG samples, unrelated…
A unified catalog of 14,062 microbial species reference genomes provides new insight into the gut microbiota in high-altitude mammals | Microbiome
Zhang Z, Xu D, Wang L, Hao J, Wang J, Zhou X, et al. Convergent evolution of rumen…
Host species and geographic location shape microbial diversity and functional potential in the conifer needle microbiome | Microbiome
Addison S, Armstrong C, Wigley K, Hartley R, Wakelin S. What matters most? Assessment of within-canopy factors influencing…
High-resolution profiling of bacterial and fungal communities using pangenome-informed taxon-specific long-read amplicons | Microbiome
Song S, Liu Y, Wang NR, Haney CH. Mechanisms in plant-microbiome interactions: lessons from model systems. Curr Opin…
Natural sex reversal imparts permanent compositional changes to the swamp eel gonadal microbiome | Microbiome
Fish maintenance and trial design The sourcing of swamp eel and the rearing procedures employed in this study…
World Record Set For Fastest Genome Sequencing | Health
Key Takeaways Researchers have set a new world record for fastest whole human genome sequencing The team completed…
World Record Set For Fastest Genome Sequencing | Health
Key Takeaways Researchers have set a new world record for fastest whole human genome sequencing The team completed…
SPAmix: a scalable, accurate, and universal analysis framework for large-scale genetic association studies in admixed populations | Genome Biology
Model residuals of linear regression and logistic regression Linear regression and logistic regression are regular models to fit…
SAGPEK: fast and flexible approach to identify genotypes of Sanger sequencing data | BMC Bioinformatics
Software architecture SAGPEK mainly processes Sanger sequencing results of two kinds of samples: diploids such as humans and…
A novel gene expression stability metric to unveil homeostasis and regulation | Genome Biology
K-proportion and gene homeostasis Z-Index identify regulatory genes As cells of the same type and in the same…
Incorporating additive genetic effects and linkage disequilibrium information to discover gene-environment interactions using BV-LDER-GE | Genome Biology
Model overview We consider the following model to incorporate both additive and interaction effects: $${Y}_{i}={\sum }_{j=1}^{M}{G}_{ji}{\beta }_{j}+{\sum }_{j=1}^{M}{S}_{ji}{\gamma…