Biomedicine

Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function

October 22, 2025

Institute of Medical Genetics, University of Zurich, Zurich, Switzerland Reza Asadollahi, Paranchai Boonsawat, Dennis Kraemer & Anita Rauch Faculty of Engineering and…

GGenetics

Modeling heterogeneity in single-cell perturbation states enhances detection of response eQTLs

October 21, 2025

Cohorts We used published data (GEO accession no. GSE162632) to study the effect of 12 h of ex vivo…

GGenetics

Genetic susceptibility to caffeine intake and metabolism: a systematic review | Journal of Translational Medicine

October 19, 2025

Coffee and Caffeine Genetics Consortium, Cornelis MC, Byrne EM, et al. Genome-wide meta-analysis identifies six novel loci associated…

GGenetics

Association of genetic variants in m1A modification core genes and neuroblastoma risk | BMC Cancer

October 18, 2025

Park JR, Kreissman SG, London WB, Naranjo A, Cohn SL, Hogarty MD, et al. Effect of tandem autologous…

GGenetics

Redefining cellular reprogramming with advanced genomic technologies

October 18, 2025

Briggs, R. & King, T. J. Transplantation of living nuclei from blastula cells into enucleated Frogs’ eggs. Proc.…

HHealthcare

When helpfulness backfires: LLMs and the risk of false medical information due to sycophantic behavior

October 17, 2025

To evaluate language models across varying levels of drug familiarity, we used the RABBITS30 dataset, which includes 550…

HHealth

From dysbiosis to longevity: a narrative review into the gut microbiome’s impact on aging | Journal of Biomedical Science

October 12, 2025

Partridge L, Deelen J, Slagboom PE. Facing up to the global challenges of ageing. Nature. 2018;561:45–56. Article PubMed …

GGenetics

Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health

October 11, 2025

Ethics Our research complies with all relevant ethical regulations. All studies included in this research were approved by…

GGenetics

Nucleotide dependency analysis of genomic language models detects functional elements

October 11, 2025

SpeciesLM training For SpeciesLM metazoa, we obtained metazoan genomes comprising 494 different species from the Ensembl 110 database36.…

GGenetics

October 10, 2025

Jeffreys, A. J., Wilson, V. & Thein, S. L. Individual-specific ‘fingerprints’ of human DNA. Nature 316, 76–79 (1985).…

HHealthcare

Generative artificial intelligence in medicine

October 6, 2025

Bengesi, S. et al. Advancements in generative AI: a comprehensive review of GANs, GPT, autoencoders, diffusion model, and…

HHealth

Genetic mutation in some East Asians linked to aldehyde storm and increased liver disease risk

October 6, 2025

Metabolic dysfunction-associated steatotic liver disease is the most common liver disease in the world, affecting about one third…

Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function

Modeling heterogeneity in single-cell perturbation states enhances detection of response eQTLs

Genetic susceptibility to caffeine intake and metabolism: a systematic review | Journal of Translational Medicine

Association of genetic variants in m1A modification core genes and neuroblastoma risk | BMC Cancer

Redefining cellular reprogramming with advanced genomic technologies

When helpfulness backfires: LLMs and the risk of false medical information due to sycophantic behavior

From dysbiosis to longevity: a narrative review into the gut microbiome’s impact on aging | Journal of Biomedical Science

Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health

Nucleotide dependency analysis of genomic language models detects functional elements

Forensic genetics in the omics era

Generative artificial intelligence in medicine

Antihypertensive and lipid-lowering drugs show efficacy against steatotic liver disease