Redefining cellular reprogramming with advanced genomic technologies
Briggs, R. & King, T. J. Transplantation of living nuclei from blastula cells into enucleated Frogs’ eggs. Proc.…
When helpfulness backfires: LLMs and the risk of false medical information due to sycophantic behavior
To evaluate language models across varying levels of drug familiarity, we used the RABBITS30 dataset, which includes 550…
From dysbiosis to longevity: a narrative review into the gut microbiome’s impact on aging | Journal of Biomedical Science
Partridge L, Deelen J, Slagboom PE. Facing up to the global challenges of ageing. Nature. 2018;561:45–56. Article PubMed …
Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health
Ethics Our research complies with all relevant ethical regulations. All studies included in this research were approved by…
Nucleotide dependency analysis of genomic language models detects functional elements
SpeciesLM training For SpeciesLM metazoa, we obtained metazoan genomes comprising 494 different species from the Ensembl 110 database36.…
Forensic genetics in the omics era
Jeffreys, A. J., Wilson, V. & Thein, S. L. Individual-specific ‘fingerprints’ of human DNA. Nature 316, 76–79 (1985).…
Generative artificial intelligence in medicine
Bengesi, S. et al. Advancements in generative AI: a comprehensive review of GANs, GPT, autoencoders, diffusion model, and…
Antihypertensive and lipid-lowering drugs show efficacy against steatotic liver disease
Metabolic dysfunction-associated steatotic liver disease is the most common liver disease in the world, affecting about one third…
Effect of tumor draining lymph nodes in the formation and maturation of tertiary lymphoid structure in patients with lung adenocarcinoma | BMC Cancer
Siegel RL, Miller KD, Wagle NS, Jemal A. Cancer statistics, 2023. CA Cancer J Clin. 2023;73:17–48. https://doi.org/10.3322/caac.21763. Article …
A genetic map of human metabolism across the allele frequency spectrum
Study design The UKB is a prospective cohort study from the UK that contains more than 500,000 volunteers…
Operationalizing machine-assisted translation in healthcare
Rawal, S. et al. Association between limited English proficiency and revisits and readmissions after hospitalization for patients with…
Spatial architecture of development and disease
Bressan, D., Battistoni, G. & Hannon, G. J. The dawn of spatial omics. Science 381, eabq4964 (2023). Article …