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Browsing Tag

Blood

206 posts
HHealth
Etomidate proves safer than ketamine for emergency intubations
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Etomidate proves safer than ketamine for emergency intubations

  • December 13, 2025
Doctors treating seriously ill patients in an emergency setting may want to give the sedative etomidate, rather than ketamine,…
HHealth
Excessive amounts of visceral fat tied to faster heart aging
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Nighttime heart attacks cause less damage due to neutrophil circadian rhythms

  • December 13, 2025
Heart attacks that occur at night are less severe than those that strike during the day. A new…
NNutrition
Study: Vitamin B12: A Comprehensive Review of Natural vs Synthetic Forms of Consumption and Supplementation. Image Credit: Fida Olga / Shutterstock
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Why the form of vitamin B12 you take may matter more than your intake

  • December 12, 2025
A new scientific review weighs natural and synthetic forms of vitamin B12, revealing where methylcobalamin may outperform standard…
HHealth
Cellular responses to ischemic reperfusion injury in young vs older donor organs. During ischemia, the deprivation of oxygen and nutrients leads to mitochondrial dysfunction and energy loss. In young cells, mitochondrial resilience helps sustain ATP production, ameliorating damage. Old cells, in contrast, experience significant ATP depletion, relying heavily on anaerobic metabolism, which leads to lactate buildup, pH reduction, and cellular stress. Upon reperfusion, the restoration of blood flow triggers oxidative stress as mitochondria generate excessive reactive oxygen species (ROS). Young cells compensate for those events through robust antioxidant systems, maintaining cellular integrity. Conversely, in old cells, impaired antioxidant defenses result in unregulated ROS production, furthermore damaging membranes, organelles, and DNA. Additionally, old cells release pro-inflammatory genes, amplifying local inflammation. Consequences are particularly severe in aged vascular endothelial cells, with ion pump dysfunction (e.g., Na⁺/K⁺ ATPase) causing ionic imbalances and cellular edema. This disruption exacerbates ischemic injury, progressing to irreversible damage. In contrast, young cells effectively resolve edema and inflammation through mechanisms that include macrophage945 mediated clearance of Damage-Associated Molecular Patterns (DAMPs) and anti-inflammatory cytokine release (e.g., IL-10 and TGF-β), allowing recovery and tissue repair. In old cells, persistent ROS generation, unresolved inflammation, and DAMP accumulation lead to irreversible inflammation, organelle collapse, and eventual cell death. Created in BioRender. Kayumov, M. (2025) https://BioRender.com/m23u7ro .
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Scientists outline how organ rejuvenation strategies could solve the donor shortage

  • December 12, 2025
New insights into cellular aging, perfusion technologies, and senescence-targeting treatments show how aging organs could be revived, turning…
HHealth
New approach doubles chemotherapy effectiveness by targeting cancer cell memory
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AI uncovers how DNA architecture failures trigger blood cancer

  • December 11, 2025
Cancer isn’t just about broken genes-it’s about broken architecture. Imagine a city where roads suddenly vanish, cutting off…
SScience
Beta blockers reduce mortality and heart failure in MI patients with mildly reduced ejection fraction
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Collaborative project seeks safer therapies for ischemia and reperfusion injury

  • December 11, 2025
Southwest Research Institute (SwRI) and Trinity University will improve a prodrug, a compound activated in the body, to…
TTechnology
Study: Different coffee consumption patterns affect HbA1c via propionic acid-producing gut microbiota. Image Credit: Rabizo Anatolii / Shutterstock
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Filtered coffee shows a causal link to healthier HbA1c levels

  • December 11, 2025
A large genetic study reveals that how coffee is prepared matters, linking filtered coffee to improved glycaemic control…
NNutrition
Vitamin C (ascorbate) is found in all skin compartments. Pullar et al. carried out a comprehensive investigation to establish the relationship between plasma and skin ascorbate levels, with a focus on the major skin compartments. Image credit: Pullar et al., doi: 10.1016/j.jid.2025.10.587.
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Collagen Production and Skin Renewal Directly Respond to Amount of Vitamin C We Consume: Study

  • December 10, 2025
Skin vitamin C levels are closely tied to levels of the vitamin in the blood (plasma) and can…
HHealth
Cystic fibrosis patients on triple-drug therapy can safely reduce daily lung treatments
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Enterprise Therapeutics publishes results of Phase 1 study of ETD001, a novel inhaled ENaC blocker for treatment of Cystic Fibrosis, in The Journal of Cystic Fibrosis

  • December 9, 2025
Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve…
HHealth
Study: The relationship between serum total alkaline phosphatase and risk of osteoporosis: a cross-sectional study. Image Credit: Javier Regueiro / Shutterstock
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Routine blood test may flag hidden osteoporosis risk, study finds

  • December 9, 2025
Common blood test results may offer an early clue to bone loss, suggesting that alkaline phosphatase levels could…
HHealth
Study: Dietary iron deficiency impairs effector function of memory T cells following influenza infection. Image Credit: Corona Borealis Studio  / Shutterstock
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Poor dietary iron weakens lung memory T cells after flu infection

  • December 8, 2025
Even when immune memory cells form in the lung after influenza infection, insufficient dietary iron leaves them less…
HHealth
Calcium supplements do not prevent pre-eclampsia, large trials show no meaningful benefit
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Calcium supplements do not prevent pre-eclampsia, large trials show no meaningful benefit

  • December 8, 2025
A new Cochrane systematic review of 10 randomised trials involving over 37,000 pregnant women found that calcium supplementation…
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