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Browsing Tag

Cell

207 posts
SScience
Middle precentral gyrus plays key role in orchestrating speech movements
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Engineered sensor reveals the brain’s hidden chemical conversations

  • December 24, 2025
Scientists have engineered a protein able to record the incoming chemical signals of brain cells (as opposed to…
SScience
Study reveals how aging reshapes protein chemistry in the brain
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Cells balance protein production and removal through passive adaptation

  • December 23, 2025
Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from…
HHealth
New approach doubles chemotherapy effectiveness by targeting cancer cell memory
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Reframing the role of MCL1 in cancer signaling and metabolism

  • December 23, 2025
A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD…
SScience
New insights reveal persistent genome structure during cell division
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Opposing protein forces fine tune mRNA stability in human cells

  • December 17, 2025
A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders…
HHealth
Adding progesterone to gender-affirming hormone therapy improves breast growth for transgender people
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Researchers discover that a hormone can access the brain by hitchhiking

  • December 16, 2025
Researchers at Touro University Nevada have discovered that tiny particles in the blood, called extracellular vesicles (EVs), are…
SScience
Middle precentral gyrus plays key role in orchestrating speech movements
Read More

Bioluminescent tool illuminates single-cell activity in living brains

  • December 13, 2025
A decade ago, a group of scientists had the literally brilliant idea to use bioluminescent light to visualize…
HHealth
SN101 iPSC-derived therapy relieves chronic pain and preserves joints
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SN101 iPSC-derived therapy relieves chronic pain and preserves joints

  • December 13, 2025
SereNeuro Therapeutics, a preclinical biotechnology company developing non-opioid pain therapies, unveiled new data today on a novel approach…
HHealth
New computer program mimics cell behavior for faster medical discoveries
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UC Irvine receives funding for clinical trial of neural stem cell therapy for Huntington’s disease

  • December 13, 2025
Leslie M. Thompson, Donald Bren Professor of psychiatry and human behavior as well as neurobiology and behavior at…
HHealth
Excessive amounts of visceral fat tied to faster heart aging
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Human heart organoids enable new therapies for atrial fibrillation

  • December 13, 2025
Though an estimated 60 million people around the world have atrial fibrillation, or A-fib, a type of irregular…
HHealth
Excessive amounts of visceral fat tied to faster heart aging
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Nighttime heart attacks cause less damage due to neutrophil circadian rhythms

  • December 13, 2025
Heart attacks that occur at night are less severe than those that strike during the day. A new…
NNutrition
Study: Vitamin B12: A Comprehensive Review of Natural vs Synthetic Forms of Consumption and Supplementation. Image Credit: Fida Olga / Shutterstock
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Why the form of vitamin B12 you take may matter more than your intake

  • December 12, 2025
A new scientific review weighs natural and synthetic forms of vitamin B12, revealing where methylcobalamin may outperform standard…
HHealth
Cellular responses to ischemic reperfusion injury in young vs older donor organs. During ischemia, the deprivation of oxygen and nutrients leads to mitochondrial dysfunction and energy loss. In young cells, mitochondrial resilience helps sustain ATP production, ameliorating damage. Old cells, in contrast, experience significant ATP depletion, relying heavily on anaerobic metabolism, which leads to lactate buildup, pH reduction, and cellular stress. Upon reperfusion, the restoration of blood flow triggers oxidative stress as mitochondria generate excessive reactive oxygen species (ROS). Young cells compensate for those events through robust antioxidant systems, maintaining cellular integrity. Conversely, in old cells, impaired antioxidant defenses result in unregulated ROS production, furthermore damaging membranes, organelles, and DNA. Additionally, old cells release pro-inflammatory genes, amplifying local inflammation. Consequences are particularly severe in aged vascular endothelial cells, with ion pump dysfunction (e.g., Na⁺/K⁺ ATPase) causing ionic imbalances and cellular edema. This disruption exacerbates ischemic injury, progressing to irreversible damage. In contrast, young cells effectively resolve edema and inflammation through mechanisms that include macrophage945 mediated clearance of Damage-Associated Molecular Patterns (DAMPs) and anti-inflammatory cytokine release (e.g., IL-10 and TGF-β), allowing recovery and tissue repair. In old cells, persistent ROS generation, unresolved inflammation, and DAMP accumulation lead to irreversible inflammation, organelle collapse, and eventual cell death. Created in BioRender. Kayumov, M. (2025) https://BioRender.com/m23u7ro .
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Scientists outline how organ rejuvenation strategies could solve the donor shortage

  • December 12, 2025
New insights into cellular aging, perfusion technologies, and senescence-targeting treatments show how aging organs could be revived, turning…
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