Research Reveals How Disordered Protein Regions Contribute to Cancer-Causing Condensates
Newswise — (MEMPHIS, Tenn. – December 3, 2025) Fusion oncoproteins arise when a gene fuses with another gene…
Cutting-edge treatments in amyotrophic lateral sclerosis: the role of molecular pathogenesis in targeted therapies | Stem Cell Research & Therapy
Feldman EL, Goutman SA, Petri S, Mazzini L, Savelieff MG, Shaw PJ, et al. Amyotrophic lateral sclerosis. Lancet.…
Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering
All the cells in an organism have the exact same genetic sequence. What differs across cell types is…
Efficacy of Extracellular Vesicles Derived From Mesenchymal Stromal Cells in Regulating Senescence: In Vitro and in vivo Insights
BACKGROUND Newswise — Extracellular vesicles derived from mesenchymal stromal cells (MSC-EVs) can be used for anti-aging therapy and…
Common IVF test misses some genetic abnormalities in embryos
Coloured light micrograph of a human embryo after in vitro fertilisation ZEPHYR/SCIENCE PHOTO LIBRARY During in vitro fertilisation…
Researchers discover new genetic cause of hereditary optic atrophy
A research team from the Medical University of Vienna and the Medical University of Graz has discovered a…
Interactions between LncRNAs and MAPK signaling pathways in the pathogenesis of breast cancer | Cancer Cell International
Filho AM, Laversanne M, Ferlay J, Colombet M, Piñeros M, Znaor A, et al. The GLOBOCAN 2022 cancer…
CellNavi predicts genes directing cellular transitions by learning a gene graph-enhanced cell state manifold
Input embeddings In CellNavi, we use single-cell raw count matrices as the only input. Specifically, the single-cell sequencing…
The Surprising Way Parents Transfer Longevity to Offspring
Research in C. elegans shows that longevity-related changes in lysosomes can be passed from parents to offspring. The…
Tiny Arctic Organisms Are Defying the Rules of Biology
Image of an Arctic diatom, showing the actin filaments that run down its middle and enable its skating…
Understanding how lipids activate LC3-associated phagocytosis
LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles. It plays a…
Scientists Solve Medical Mystery Behind Rare Multi-Organ Disease
Scientists have uncovered the genetic cause of a mysterious multi-organ disease, tracing it to faulty versions of the…