Thiostrepton suppresses rhabdomyosarcoma progression by targeting the PI3K–AKT pathway
Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.…
TROP2 identified as a promising therapeutic target for renal medullary carcinoma
Researchers at The University of Texas MD Anderson Cancer Center, in collaboration with BostonGene, conducted the largest and…
Stem cells show promise in preventing post-heart attack heart failure
Patients with weak heart function who receive stem cell therapy shortly after a heart attack are at lower…
The role of epigenetics in memory expression
Our experiences leave traces in the brain, stored in small groups of cells called “engrams”. Engrams are thought…
Eating peanuts while pregnant may influence how a child’s genes respond to breastfeeding
Researchers found that mothers who ate both peanuts and peanut butter during pregnancy had children with distinct DNA…
New insight into TRPM3 heat sensor reveals how the body detects temperature
The ability to sense heat protects the body from burns and injury. But how the body actually feels…
Disruption of glial circadian rhythms linked to Alzheimer’s disease progression
Alzheimer’s disease is notorious for scrambling patients’ daily rhythms. Restless nights with little sleep and increased napping during…
Common test to assess viability of IVF embryos may be flawed
A test deployed in many fertility clinics to assess the viability of embryos for use in IVF is…
Epigenetic editing enables safer and more effective T cell therapies
Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic editing platform that…
A new way to monitor chemotherapy drug behavior inside cells
Scientists have made incredible progress in developing cancer therapies that help patients across cancer types. However, they face…
New insights into how the blood-brain barrier safeguards the brain
By decoding the blood-brain barrier’s intricate structure and function, researchers are paving the way for new therapies that…
Researchers develop a new approach for treating children with neuroblastoma
A research team from the University of Zurich and the University Children’s Hospital Zurich has developed a new…