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Browsing Tag

Cytokine

16 posts
HHealth
Tumor environments sculpt diverse natural killer cells for cancer therapies
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Tumor environments sculpt diverse natural killer cells for cancer therapies

  • September 4, 2026
For decades, natural killer (NK) cells have been classified into two main groups based on surface markers: one…
HHealth
Study: The impact of dietary fibres on gut microbiome of young children: insights from in vitro experiments and an observational cohort. Image Credit: Helena Nechaeva / Shutterstock
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Could the type of fiber children eat matter for their developing gut microbiome?

  • September 1, 2026
From microbial diversity to gut barrier function, researchers are uncovering how individual fiber types may interact differently with…
HHealth
Study: Thymulin restrains age-associated myeloid inflammation and enhances cancer immunotherapy. Image Credit: Lightspring
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Thymulin curbs age-related inflammation and slows breast tumors in mice

  • July 23, 2026
A thymus-derived peptide reduced inflammatory immune activity and improved immunotherapy responses in aged mice, suggesting a potential strategy…
TTechnology
Nasal viruses may drive allergic rhinitis, and ribavirin shows early promise as a targeted spray treatment
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Nasal viruses may drive allergic rhinitis, and ribavirin shows early promise as a targeted spray treatment

  • June 29, 2026
A new study suggests that clearing symptom-driving nasal viruses could calm allergic inflammation and open a fresh treatment…
HHealth
Middle precentral gyrus plays key role in orchestrating speech movements
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Cytokine-armored CAR-T cell therapy successfully attacks aggressive brain tumors in mice

  • May 20, 2026
Scientists at the UCLA Health Jonsson Comprehensive Cancer Center have developed a new cytokine-armored CAR-T cell therapy that helps the…
HHealth
Exercise helps improve sleep and mood in smokers over 40
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Anti-inflammatory drug tocilizumab shows promise for difficult-to-treat depression

  • May 20, 2026
Immunotherapy could be a promising new treatment option for patients with difficult-to-treat depression. This is a key finding from a University…
HHealth
Young couple relaxing and sweating in hot sauna wrapped in towel. Woman and man In Sauna. Interior of Finnish sauna, classic wooden steam room with hot steam. Russian bathroom. Relax in hot Bathhouse.
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A single sauna session boosts immune cells within minutes

  • April 17, 2026
New research reveals how a brief Finnish sauna session mobilizes immune defenses within minutes, offering fresh clues into…
HHealth
Study: Immune modulation in response to coffee intake: a pilot study. Image Credit: ZeiMomArt / Shutterstock
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Study reveals coffee triggers distinct cytokine responses compared with pure caffeine

  • February 19, 2026
A controlled human study reveals that coffee’s complex chemical matrix may shape immune responses differently than pure caffeine,…
HHealth
Cellular responses to ischemic reperfusion injury in young vs older donor organs. During ischemia, the deprivation of oxygen and nutrients leads to mitochondrial dysfunction and energy loss. In young cells, mitochondrial resilience helps sustain ATP production, ameliorating damage. Old cells, in contrast, experience significant ATP depletion, relying heavily on anaerobic metabolism, which leads to lactate buildup, pH reduction, and cellular stress. Upon reperfusion, the restoration of blood flow triggers oxidative stress as mitochondria generate excessive reactive oxygen species (ROS). Young cells compensate for those events through robust antioxidant systems, maintaining cellular integrity. Conversely, in old cells, impaired antioxidant defenses result in unregulated ROS production, furthermore damaging membranes, organelles, and DNA. Additionally, old cells release pro-inflammatory genes, amplifying local inflammation. Consequences are particularly severe in aged vascular endothelial cells, with ion pump dysfunction (e.g., Na⁺/K⁺ ATPase) causing ionic imbalances and cellular edema. This disruption exacerbates ischemic injury, progressing to irreversible damage. In contrast, young cells effectively resolve edema and inflammation through mechanisms that include macrophage945 mediated clearance of Damage-Associated Molecular Patterns (DAMPs) and anti-inflammatory cytokine release (e.g., IL-10 and TGF-β), allowing recovery and tissue repair. In old cells, persistent ROS generation, unresolved inflammation, and DAMP accumulation lead to irreversible inflammation, organelle collapse, and eventual cell death. Created in BioRender. Kayumov, M. (2025) https://BioRender.com/m23u7ro .
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Scientists outline how organ rejuvenation strategies could solve the donor shortage

  • December 12, 2025
New insights into cellular aging, perfusion technologies, and senescence-targeting treatments show how aging organs could be revived, turning…
HHealth
Study: Dietary iron deficiency impairs effector function of memory T cells following influenza infection. Image Credit: Corona Borealis Studio  / Shutterstock
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Poor dietary iron weakens lung memory T cells after flu infection

  • December 8, 2025
Even when immune memory cells form in the lung after influenza infection, insufficient dietary iron leaves them less…
HHealth
Study: Association of cesarean section with asthma and atopic dermatitis in infants from the Japan Environment and Children’s Study. Image Credit: Roman Fenton / Shutterstock
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Cesarean births do not raise infant allergy risk in major Japanese cohort study

  • November 14, 2025
A nationwide Japanese cohort finds no evidence that cesarean delivery increases early-life risks of eczema, wheezing, asthma, or…
HHealth
ACC Scientific Statement 29 September 2025 Share on Inflammation and Cardiovascular Disease: 2025 ACC Scientific Statement: A Report of the American College of Cardiology
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What clinicians and families can do now

  • September 30, 2025
A new ACC scientific statement shows that cholesterol control alone is not enough; targeting inflammation with lifestyle and…
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