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Browsing Tag

drug discovery

11 posts
TTechnology
Structure of a PROTAC. The molecule links an E3 ligase-binding domain to a target protein ligand via a flexible chemical linker, enabling targeted ubiquitination and subsequent proteasomal degradation6
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PROTACs and MGDs role in drug discovery

  • September 15, 2025
Stick, tag, destroy: The science of PROTACs and MGDs Traditional drug research has focused on creating inhibitors that…
GGenetics
AI Model Finds Gene Targets and Drug Combos to Reprogram Diseased Cells
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AI Model Finds Gene Targets and Drug Combos to Reprogram Diseased Cells

  • September 10, 2025
Credit: FlashMovie/Getty Images Traditional drug discovery has often followed the “one drug, one target” paradigm—developing compounds against individual…
GGenetics
Mitochondria, illustration
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Preclinical Data Spotlights Gene with Therapeutic Potential for Barth Syndrome

  • September 6, 2025
Barth Syndrome is a rare X-linked genetic condition caused by a mutation in the Tafazzin gene, which is…
MMedication
Medicines Reimagined – Repurposing Drugs For New Indications
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Medicines Reimagined – Repurposing Drugs For New Indications

  • August 28, 2025
In a group of health-related headlines, one says “Hope for new drug approach. getty As government-supported research in…
HHealth
Transcription factors in next-gen drug discovery
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Transcription factors in next-gen drug discovery

  • August 26, 2025
Transcription Factors (TFs) are pivotal regulators of gene expression and have been implicated in a variety of diseases,…
CComputing
AI and Quantum Computing Advance Drug Discovery Amid Challenges
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AI and Quantum Computing Advance Drug Discovery Amid Challenges

  • August 12, 2025
As artificial intelligence continues to reshape industries, a recent breakthrough highlighted by the BBC underscores the accelerating pace…
GGenetics
Morphological map of under- and overexpression of genes in human cells
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Morphological map of under- and overexpression of genes in human cells

  • August 8, 2025
Mattiazzi Usaj, M. et al. High-content screening for quantitative cell biology. Trends Cell Biol. 26, 598–611 (2016). CAS …
GGenetics
Hibernation’s Hidden Healing ‘Superpowers’ Could Be Locked in Our DNA
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Hibernation’s Hidden Healing ‘Superpowers’ Could Be Locked in Our DNA

  • July 31, 2025
After spending months without eating, drinking, or moving, hibernating mammals must rebound from extreme physiological changes. Two new…
GGenetics
New genetic discovery could change how Friedreich's ataxia is diagnosed
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Australian scientists uncover new way to halt aggressive cancer growth

  • July 28, 2025
Australian researchers have discovered a promising new strategy to suppress the growth of aggressive and hard-to-treat cancers by…
GGenetics
Insmed explores a new frontier in genetic therapeutics
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Insmed explores a new frontier in genetic therapeutics

  • July 28, 2025
Nestled on the southern fringe of Cambridge within the Babraham Research Campus, US-based biopharma Insmed is laying the…
MMedication
First New PTSD Drug in Two Decades On the Horizon?
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First New PTSD Drug in Two Decades On the Horizon?

  • July 19, 2025
The Psychopharmacologic Drugs Advisory Committee of the FDA is set to meet on July 18 to consider a…
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