Combination therapy overcomes ferroptosis resistance in β-catenin-mutant hepatocellular carcinoma
Background and aims The aberrant activation of the mTOR pathway and its crosstalk with other signaling cascades represent…
Melatonin improves skin flap survival by reducing ferroptosis
Random-pattern skin flaps are widely used to repair defects caused by trauma, burns, tumor removal, and other injuries…
Western diet weakens the gut’s nervous system through iron-dependent damage
A new study suggests that saturated fat exposure may damage the gut’s own nervous system by triggering iron-dependent…
Study shows how TAF1 regulates ferroptosis in cancer cells
Ferroptosis has become a promising area in cancer research because it may provide a way to target tumor…
Tumor microenvironment drives resistance to ferroptosis in pancreatic cancer
Tumors driven by cancer-driving KRAS mutations are often susceptible to ferroptosis, a type of cell death that can…
Triaptosis-based therapeutic innovations could offer renewed hope for cancer patients
Cancer remains one of the most critical global public health challenges, exerting profound social, economic, and clinical burdens…
Trojan horse strategy using cesium nanosalts shows powerful anti-cancer effects
Recently, a team led by Academician Hongjie Zhang, Researcher Shuyan Song, Associate Researcher Pengpeng Lei, and Dr. Ran An…
Genetic mutation in some East Asians linked to aldehyde storm and increased liver disease risk
Researchers have identified the mechanism by which a common genetic mutation increases liver disease risk. Their findings suggest…