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Browsing Tag

Gene Function

27 posts
GGenetics
Bryophytes hold a larger gene family space than vascular plants
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Bryophytes hold a larger gene family space than vascular plants

  • September 23, 2025
Kenrick, P. & Crane, P. R. The origin and early evolution of plants on land. Nature 389, 33–39…
GGenetics
Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects
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Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects

  • September 18, 2025
Abul-Husn, N. S. & Kenny, E. E. Personalized medicine and the power of electronic health records. Cell 177,…
GGenetics
Is enhancer-driven gene regulation all wrapped up?
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Is enhancer-driven gene regulation all wrapped up?

  • September 17, 2025
Symmons, O. et al. The Shh topological domain facilitates the action of remote enhancers by reducing the effects…
GGenetics
Regulatory genome annotation | Nature Reviews Genetics
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Regulatory genome annotation | Nature Reviews Genetics

  • September 17, 2025
Gerstein, M. B. et al. Architecture of the human regulatory network derived from ENCODE data. Nature 489, 91–100…
GGenetics
A genome-wide association analysis reveals new pathogenic pathways in gout
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A genome-wide association analysis reveals new pathogenic pathways in gout

  • September 11, 2025
Kuo, C. F. et al. Global epidemiology of gout: prevalence, incidence and risk factors. Nat. Rev. Rheumatol. 11,…
GGenetics
Multiancestry brain pQTL fine-mapping and integration with genome-wide association studies of 21 neurologic and psychiatric conditions
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Multiancestry brain pQTL fine-mapping and integration with genome-wide association studies of 21 neurologic and psychiatric conditions

  • September 9, 2025
Ethics Our study complies with all relevant ethical regulations and was approved by the institutional review boards at…
SScience
Improving broad-spectrum resistance to clubroot disease with one gene
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Improving broad-spectrum resistance to clubroot disease with one gene

  • September 5, 2025
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This…
GGenetics
Telomere attrition becomes an instrument for clonal selection in aging hematopoiesis and leukemogenesis
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Telomere attrition becomes an instrument for clonal selection in aging hematopoiesis and leukemogenesis

  • September 2, 2025
Ethical regulations This study was conducted under approved UKB application no. 56844. Clinical samples were obtained with informed…
GGenetics
Mutational landscape of triple-negative breast cancer in African American women
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Mutational landscape of triple-negative breast cancer in African American women

  • August 30, 2025
Patient population Paired tumor and normal samples from 513 self-identified AA women with TNBC were interrogated by WES.…
GGenetics
Precise modulation of BRG1 levels reveals features of mSWI/SNF dosage sensitivity
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Precise modulation of BRG1 levels reveals features of mSWI/SNF dosage sensitivity

  • August 25, 2025
BRG1 binding exhibits a linear response to its dosage In mES cells, Brg1 encodes the major catalytic subunit…
GGenetics
Temporal genomic dynamics shape clinical trajectory in multiple myeloma
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Temporal genomic dynamics shape clinical trajectory in multiple myeloma

  • August 23, 2025
Maura, F. et al. Moving from cancer burden to cancer genomics for smoldering myeloma: a review. JAMA Oncol.…
GGenetics
Imaging-based multimodal profiling of single cells with STAMP
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Imaging-based multimodal profiling of single cells with STAMP

  • August 22, 2025
Single-cell RNA sequencing (scRNA-seq) has dramatically advanced our ability to dissect complex biological systems at cellular resolution. However,…
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