Breakthrough reveals how viruses efficiently pack genetic material
Researchers at San Diego State University and Michigan State University are shedding new light on how viruses meticulously…
Nanostructures boost CRISPR delivery for genetic medicine
With the power to rewrite the genetic code underlying countless diseases, CRISPR holds immense promise to revolutionize medicine.…
Why metformin could protect the brain by rewiring mitochondria
A new study shows metformin enhances myelin repair in human-based models by tuning mitochondrial metabolism, offering hope for…
Scientists discover molecular brake that limits T cell attack on tumors
In a discovery that could expand the array of current cancer immunotherapy treatments, scientists at Harvard Medical School…
Insights into clinical features and genetic variants of Cornelia de Lange syndrome in China
Cornelia de Lange syndrome (CdLS) is a rare genetic disorder with symptoms, including facial anomalies (such as fused…
New mouse models reveal mechanisms of RP59 retinal degeneration
Retinitis pigmentosa retinal degeneration is caused by a family of hereditary mutations in nearly 100 genes that slowly…
BindCraft reimagines protein binder discovery through structural prediction
Physical interactions between proteins influence anything from cell signaling and growth to immune responses, so the ability to…
Male and female bovine embryos show distinct development paths
Cornell researchers have uncovered the genetic triggers that cause male and female bovine embryos to develop differently, as…
Shared gene signatures reveal metabolic dysfunction in liver cirrhosis and acute-on-chronic liver failure
Background and objectives Chronic liver cirrhosis (LC) and acute-on-chronic liver failure (ACLF) are interconnected hepatic disorders associated with…
Genetic variants mimicking IL-6 inhibition linked to lower cardiovascular risk
People with lower interleukin-6 activity have a reduced risk of cardiovascular diseases, a new LMU study reveals. Lowering…
Genetics and diet work together to shape daily rhythms of fat metabolism
Our bodies follow a natural 24-hour cycle known as the circadian rhythm that influences everything from sleep to metabolism.…
Mediterranean-style diet may reduce dementia risk in individuals with high genetic risk
A new study led by investigators from Mass General Brigham, Harvard T.H. Chan School of Public Health, and…