APC-deficient cancer cells rely on single enzyme for survival
A newly published study reports that APC-deficient cancer cells may depend on a single metabolic enzyme for survival,…
High-resolution study maps molecular differences across six human cortical regions
A new analysis of individual brain cells across several human brain regions reveals subtle but widespread differences in…
How the immune system may influence Alzheimer’s, Parkinson’s, and related diseases
A sweeping review shows how the brain’s immune defenses can both fight and fuel neurodegeneration, revealing why timing,…
Study shows why an apple a day may work differently for different people
A 12-week trial suggests that an apple a day may not affect everyone the same way, with baseline…
Parents’ intake of sugar substitutes may influence offspring gut biology, study finds
A new mouse study suggests that sweeteners consumed by parents may reshape gut bacteria, microbial metabolites, and metabolic…
Pseudogene lncRNAs regulate cancer stem cell behavior and signaling
Cancer stem cells (CSCs), a critical subpopulation within tumors, drive cancer initiation, progression, metastasis, relapse, and resistance to…
Fat-producing enzyme identified as key driver of damage in Parkinson’s disease
A fat-producing enzyme in brain cells may play a key role in driving damage in Parkinson’s disease and…
Cola may quickly lower pH inside orthodontic clear aligners and shift oral bacteria within hours
A 24-hour microbiome study suggests that cola can rapidly disturb the aligner-tooth microenvironment, and that removing aligners before…
Study identifies a common hidden genetic cause of neurodevelopmental disorder in children
A major genetic study has uncovered a surprisingly common recessive cause of neurodevelopmental disorder, revealing how hidden changes…
Stard7 plays unexpected role in intestinal cancer development
A new study led by researchers at the University of Liège highlights the unexpected role of Stard7 in…
How could bisphenol A raise depression risk? Study identifies six key molecular targets
Researchers combined genetic epidemiology, transcriptomics, molecular docking, and mouse experiments to show how a common endocrine-disrupting chemical may…
Heart failure and atrial fibrillation share underlying genetic and molecular mechanisms
New research published in Nature Cardiovascular Research reveals that heart failure and atrial fibrillation share underlying genetic and molecular mechanisms, suggesting…