New integrated framework advances precision surgery for liver cancer
Hepatocellular carcinoma is the sixth most common malignancy and the third leading cause of cancer-related death globally. Despite…
Combination therapy overcomes ferroptosis resistance in β-catenin-mutant hepatocellular carcinoma
Background and aims The aberrant activation of the mTOR pathway and its crosstalk with other signaling cascades represent…
Daily tomatoes lowered a key marker of liver fat in MASLD trial
A six-week tomato-rich diet outperformed a tomato-free diet on an important marker of hepatic steatosis, pointing to a…
Experts reframe steatotic liver disease as a dynamic continuum
The classification of steatotic liver disease (SLD) is undergoing a major conceptual transformation. In a recent article published…
EVA1A regulates fatty acid transporter CD36 in fatty liver disease
Metabolic Dysfunction-Associated Steatotic Liver Disease（MASLD） is characterized by excessive accumulation of lipids in hepatocytes and is closely associated…
University of Missouri launches first on-campus radiopharmaceutical clinical trial
In a major leap for cancer care at the University of Missouri, the School of Medicine and MU…
Study reports the world’s first genetically engineered pig-to-human liver xenotransplantation
An important new study in the Journal of Hepatology, published by Elsevier, reports the world’s first auxiliary liver…
Study identifies key molecular and clinical biomarkers for MASLD
Background and aims The causal biomarkers for metabolic dysfunction-associated steatotic liver disease (MASLD) and their clinical value remain…
ATOX1 drives hepatocellular carcinoma progression through c-Myb and PI3K/AKT activation
Background and aims Despite advancements in diagnostic and therapeutic strategies, hepatocellular carcinoma (HCC) remains a leading cause of…