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Browsing Tag

Human Genetics

53 posts
GGenetics
Incorporating additive genetic effects and linkage disequilibrium information to discover gene-environment interactions using BV-LDER-GE | Genome Biology
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Incorporating additive genetic effects and linkage disequilibrium information to discover gene-environment interactions using BV-LDER-GE | Genome Biology

  • October 3, 2025
Model overview We consider the following model to incorporate both additive and interaction effects: $${Y}_{i}={\sum }_{j=1}^{M}{G}_{ji}{\beta }_{j}+{\sum }_{j=1}^{M}{S}_{ji}{\gamma…
GGenetics
Spatial architecture of development and disease
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Spatial architecture of development and disease

  • October 1, 2025
Bressan, D., Battistoni, G. & Hannon, G. J. The dawn of spatial omics. Science 381, eabq4964 (2023). Article …
GGenetics
Limited overlap between genetic effects on disease susceptibility and disease survival
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Limited overlap between genetic effects on disease susceptibility and disease survival

  • September 30, 2025
Ethics statement This study was conducted in compliance with the relevant ethical guidelines and approved by the appropriate…
TTechnology
Genome of the green-head ant, Rhytidoponera metallica, reveals mechanisms of toxin evolution in a genetically hyper-diverse eusocial species | Genome Biology
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Genome of the green-head ant, Rhytidoponera metallica, reveals mechanisms of toxin evolution in a genetically hyper-diverse eusocial species | Genome Biology

  • September 26, 2025
Genome from a single ant resolves allelic and paralogous toxin diversity Assembling the HiFi reads obtained from DNA…
GGenetics
Bryophytes hold a larger gene family space than vascular plants
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Bryophytes hold a larger gene family space than vascular plants

  • September 23, 2025
Kenrick, P. & Crane, P. R. The origin and early evolution of plants on land. Nature 389, 33–39…
GGenetics
Fueling chromosomal gene diversification and artificial evolution with CRISPR | Genome Biology
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Fueling chromosomal gene diversification and artificial evolution with CRISPR | Genome Biology

  • September 23, 2025
Wilson DS, Keefe AD. Random mutagenesis by PCR. Curr Protoc Mol Biol. 2001;51:8–3. Google Scholar  Reetz MT, Wu…
GGenetics
Regulation of heterosis-associated gene expression complementation in maize hybrids | Genome Biology
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Regulation of heterosis-associated gene expression complementation in maize hybrids | Genome Biology

  • September 22, 2025
Plant genetic resources The IBM-RIL syn. 4 population [19] represents a collection of highly diversified genotypes with respect…
SScience
Genomics will forever reshape forensic science and criminal justice | Genome Biology
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Genomics will forever reshape forensic science and criminal justice | Genome Biology

  • September 22, 2025
Historically, genomics and forensic science have progressed along distinct trajectories. Genomics, driven by large-scale initiatives like the Human…
GGenetics
Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects
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Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects

  • September 18, 2025
Abul-Husn, N. S. & Kenny, E. E. Personalized medicine and the power of electronic health records. Cell 177,…
GGenetics
Is enhancer-driven gene regulation all wrapped up?
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Is enhancer-driven gene regulation all wrapped up?

  • September 17, 2025
Symmons, O. et al. The Shh topological domain facilitates the action of remote enhancers by reducing the effects…
GGenetics
Regulatory genome annotation | Nature Reviews Genetics
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Regulatory genome annotation | Nature Reviews Genetics

  • September 17, 2025
Gerstein, M. B. et al. Architecture of the human regulatory network derived from ENCODE data. Nature 489, 91–100…
GGenetics
A genome-wide association analysis reveals new pathogenic pathways in gout
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A genome-wide association analysis reveals new pathogenic pathways in gout

  • September 11, 2025
Kuo, C. F. et al. Global epidemiology of gout: prevalence, incidence and risk factors. Nat. Rev. Rheumatol. 11,…
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