Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…
A GP guide to molecular testing in lung cancer
Need to know: Lung cancer remains a significant health challenge in Australia, being the fifth most commonly diagnosed…
Having children and breastfeeding reduces breast cancer risk by triggering immune system, study finds
One of the earliest clues that having children may help to protect women against breast cancer came from…
CRATERs identified as key sites for T cell-mediated tumor destruction
Like the surface of the moon, new research published today in Cell finds the existence of craters on…
Lung cancer researchers identify ‘breakthrough’ patterns predictive of treatment success
Researchers have discovered a way to predict whether patients with lung cancer will respond to expensive immunotherapy treatment…
Early trial finds promise for avelumab and radiation in treating leptomeningeal disease
Researchers at Moffitt Cancer Center have reported encouraging results from a phase 1B clinical trial showing that the…
Radiomics significantly outperforms clinical models for predicting NPC treatment outcome
Nasopharyngeal carcinoma (NPC) is a highly aggressive malignancy, with most patients presenting at locally advanced stages. While immune…
Immunotherapy could treat some psychiatric syndromes
When a person is suffering with psychiatric symptoms we don’t typically look to the immune system for clues.…
Scientists discover molecular brake that limits T cell attack on tumors
In a discovery that could expand the array of current cancer immunotherapy treatments, scientists at Harvard Medical School…
Melbourne mother says her medical insurer won’t cover the treatment that could save her life
Melbourne resident Zohreh Sajjad has been diagnosed with an aggressive cancer but her health insurer, Medibank, is refusing…
New method uncovers how extracellular vesicles impact immune response in cancer
Certain types of biochemical processes can impair the immune system’s ability to recognize and kill cancer cells. Purdue…
Cancer cells break down nerve covers causing immune exhaustion and therapy resistance
Cancer cells can break down the protective covers around nerves, causing nerve injury that triggers chronic inflammation leading…