Revealing an invisible kinase state that accounts for vital biological function
This ADP/ATP turnover needs to happen rapidly; otherwise, the kinase moves away too soon, and the target protein…
Researchers identify a previously unknown cellular mechanism crucial to coronavirus replication
The discovery could serve as a starting point for antiviral strategies. A research team at Ruhr University Bochum,…
Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…
Eating peanuts while pregnant may influence how a child’s genes respond to breastfeeding
Researchers found that mothers who ate both peanuts and peanut butter during pregnancy had children with distinct DNA…
Why metformin could protect the brain by rewiring mitochondria
A new study shows metformin enhances myelin repair in human-based models by tuning mitochondrial metabolism, offering hope for…
How dietary formaldehyde links to worsening diabetes and memory loss
A new review reveals how everyday foods and hidden exposures to formaldehyde may fuel insulin resistance and chip…
Metformin’s blood sugar control starts in the brain, not just the liver, study finds
Scientists uncover how low-dose metformin targets brain pathways to lower blood sugar, opening fresh avenues for safer and…
Blocking GAPDH aggregation protects brain cells and opens new path for stroke therapy
A novel study reveals that targeting a single protein’s aggregation can dramatically reduce brain injury after stroke, potentially…