Harnessing “DNA surgery” to develop therapeutic medicines for genetic liver and heart diseases
Genome editing is increasingly recognzed as a leading frontier in biomedical research and an essential driver of healthcare…
Genetic variant linked to liver injury after chemotherapy in colorectal cancer patients
A new international study led by Mayo Clinic researchers has identified a genetic factor that may explain why some patients…
Novel biosensing platform provides quantitative graded evaluation of mild to severe liver injury
Real-time monitoring of key biomarkers is a critical prerequisite for early disease diagnosis and personalized therapy. Early detection…
Study identifies key molecular and clinical biomarkers for MASLD
Background and aims The causal biomarkers for metabolic dysfunction-associated steatotic liver disease (MASLD) and their clinical value remain…
Intravenous lactate raises pro-BDNF levels similar to high intensity workouts
Science has confirmed what sports lovers have always known from experience: exercise is good for the brain. It…
Genetic study shows dual GIPR/GLP1R action curbs binge alcohol use
New genetic evidence suggests that targeting GIPR and GLP1R could reduce harmful drinking patterns while improving liver and…
Genetic mutation in some East Asians linked to aldehyde storm and increased liver disease risk
Researchers have identified the mechanism by which a common genetic mutation increases liver disease risk. Their findings suggest…
Experts warn tiny plastics in arteries may raise heart attack risk
Experts reveal how plastic particles lodged in arteries could heighten heart disease risk, demanding urgent attention from clinicians…
Neuritin 1 unlocks new pathway to treat obesity without reducing food intake
Is it possible to treat obesity without reducing food intake? A new study co-led by Dr. Antonio Zorzano…
Probiotic enhances cholesterol drug efficacy but raises safety concerns at high doses
A recent study published in Engineering has shed light on the complex interactions between probiotics and drugs, particularly…
Targeting gut signaling protein may protect against alcohol-related liver damage
Alcohol-associated liver disease (ALD) is a major cause of liver transplantation and death worldwide, and its impact is…
Shared gene signatures reveal metabolic dysfunction in liver cirrhosis and acute-on-chronic liver failure
Background and objectives Chronic liver cirrhosis (LC) and acute-on-chronic liver failure (ACLF) are interconnected hepatic disorders associated with…