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Browsing Tag

Lungs

31 posts
HHealth
Hidden fat inside the abdomen and liver may damage arteries
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Transcatheter valve-in-valve procedure improves short-term outcomes in high-risk patients

  • March 30, 2026
In patients with a poorly functioning bioprosthetic mitral valve in the heart, a minimally invasive procedure to insert…
HHealth
Simple UV technology reduces the number of respiratory infections in aged care facilities
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Major UK clinical trial finds surfactant therapy ineffective for severe bronchiolitis

  • March 23, 2026
A major UK-led clinical trial has found that a treatment commonly used to help premature babies breathe offers…
HHealth
Diagram summarising the key domains within human cognition.
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Air pollution may be lowering global IQ and widening inequality, researchers warn

  • March 11, 2026
Scientists argue that fine particle pollution may be harming brain health and lowering cognitive potential worldwide, with modelling…
HHealth
Immune system found to be more mobile and flexible than previously thought
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Gut microbiota-derived metabolite directly shapes immune responses in bacterial pneumonia

  • March 4, 2026
Sepsis and severe pneumonia are frequently accompanied by disruption of the gut microbiota, leading to immune dysfunction and…
MMedication
Nasal Spray Could Protect Against Range of Respiratory Bugs
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Nasal Spray Could Protect Against Range of Respiratory Bugs

  • February 22, 2026
Scientists are testing a nasal spray that aims to put lungs on alert against just about any…
HHealth
Single injection of gene therapy at birth may offer lasting protection against HIV
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$8.7 million award supports faster genetic diagnosis of lymphatic diseases

  • February 20, 2026
A team of researchers led by Columbia University Vagelos College of Physicians and Surgeons has been awarded an…
HHealth
Lungs and trachea.
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Artificial lung keeps patient alive after lung removal

  • February 5, 2026
By replacing both breathing and circulatory buffering, a novel artificial lung bought critical time after lung removal, revealed…
HHealth
Nanostructures boost CRISPR delivery for genetic medicine
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Repeated exposure to aged vape plumes could negatively impact lung health

  • January 30, 2026
Electronic cigarettes – or vapes – can release puffs of vapor in aromatic clouds. The health risks of…
HHealth
OU researchers explore how cannabis use affects recovery after head and neck cancer surgery
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Facial wound secrets revealed for scarless repair

  • January 22, 2026
Tweaking a pattern of wound healing established millions of years ago may enable scar-free injury repair after surgery…
HHealth
Cellular responses to ischemic reperfusion injury in young vs older donor organs. During ischemia, the deprivation of oxygen and nutrients leads to mitochondrial dysfunction and energy loss. In young cells, mitochondrial resilience helps sustain ATP production, ameliorating damage. Old cells, in contrast, experience significant ATP depletion, relying heavily on anaerobic metabolism, which leads to lactate buildup, pH reduction, and cellular stress. Upon reperfusion, the restoration of blood flow triggers oxidative stress as mitochondria generate excessive reactive oxygen species (ROS). Young cells compensate for those events through robust antioxidant systems, maintaining cellular integrity. Conversely, in old cells, impaired antioxidant defenses result in unregulated ROS production, furthermore damaging membranes, organelles, and DNA. Additionally, old cells release pro-inflammatory genes, amplifying local inflammation. Consequences are particularly severe in aged vascular endothelial cells, with ion pump dysfunction (e.g., Na⁺/K⁺ ATPase) causing ionic imbalances and cellular edema. This disruption exacerbates ischemic injury, progressing to irreversible damage. In contrast, young cells effectively resolve edema and inflammation through mechanisms that include macrophage945 mediated clearance of Damage-Associated Molecular Patterns (DAMPs) and anti-inflammatory cytokine release (e.g., IL-10 and TGF-β), allowing recovery and tissue repair. In old cells, persistent ROS generation, unresolved inflammation, and DAMP accumulation lead to irreversible inflammation, organelle collapse, and eventual cell death. Created in BioRender. Kayumov, M. (2025) https://BioRender.com/m23u7ro .
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Scientists outline how organ rejuvenation strategies could solve the donor shortage

  • December 12, 2025
New insights into cellular aging, perfusion technologies, and senescence-targeting treatments show how aging organs could be revived, turning…
HHealth
Cystic fibrosis patients on triple-drug therapy can safely reduce daily lung treatments
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Enterprise Therapeutics publishes results of Phase 1 study of ETD001, a novel inhaled ENaC blocker for treatment of Cystic Fibrosis, in The Journal of Cystic Fibrosis

  • December 9, 2025
Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve…
HHealth
Study: Dietary iron deficiency impairs effector function of memory T cells following influenza infection. Image Credit: Corona Borealis Studio  / Shutterstock
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Poor dietary iron weakens lung memory T cells after flu infection

  • December 8, 2025
Even when immune memory cells form in the lung after influenza infection, insufficient dietary iron leaves them less…
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