Systema: a framework for evaluating genetic perturbation response prediction beyond systematic variation
Nonparametric baselines We design two nonparametric baselines that we refer to as perturbed mean and matching mean. Perturbed…
Gut bacteria provide key to identifying colorectal cancer from stool samples
Colorectal cancer is the second leading cause of cancer death worldwide. If detected early, it can be efficiently…
Inappropriate Prescribing Tied to Mortality Risk in Seniors
TOPLINE: Older adults who were prescribed medications flagged as potentially inappropriate had an increased risk for mortality, with…
AI Tool Shows Exactly When Genes Turn On and Off
Summary: Researchers have developed an AI-powered tool called chronODE that models how genes turn on and off during…
ChronODE method offers precision in timing gene therapy treatments
A Yale research team has created a new computer tool that can pinpoint when exactly genes turn on…
Oral Minoxidil For Hair Loss Not Linked to Tachycardia
TOPLINE: In a large retrospective study of patients with androgenic alopecia or other nonscarring hair loss, treatment with…
AI Is the New Dr Google — Across the Globe
Patients arriving at appointments with researched information is not new, but artificial intelligence (AI) tools such as ChatGPT…
Hidden Door Rolls Out Literary Roleplaying Platform
Technology studio Hidden Door has opened its bookish roleplaying platform of the same name to early access, according…
Stacked ensemble model for NBA game outcome prediction analysis
This study aims to develop a predictive framework for NBA game outcomes using a machine-learning strategy based on…
How to Design Machine Learning Experiments — the Right Way
Never miss a new edition of The Variable, our weekly newsletter featuring a top-notch selection of editors’ picks,…
Fotagliptin Plus Metformin Enhances Glycemic Control in T2D
TOPLINE: Addition of fotagliptin to metformin significantly reduced A1c levels in patients with type 2 diabetes (T2D) compared…
China’s Z.ai and America’s Self-Defeating AI Strategy
China’s DeepSeek shocked the global AI community in January by building a frontier model at a fraction of…