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Browsing Tag

metformin

16 posts
HHealth
Acupuncture regulates immune function through specific neural circuit activation
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Early electroacupuncture intervention protects pancreatic function in prediabetes

  • July 21, 2026
Prediabetes refers to a metabolic state in which blood glucose is higher than normal but has not yet…
HHealth
Bacteria inside the small intestine, concept, representation. 3D illustration.
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Nine gut bacteria linked to future type 2 diabetes risk

  • July 9, 2026
A large prospective study of older Swedish adults identified specific gut bacteria and microbial functions linked to future…
HHealth
Study: Timing of Antidiabetic Medication Initiation and Risk of Cardiovascular Events and Mortality. Image Credit: Anastasiya Artcomma / Shutterstock
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Early diabetes drug treatment links to better survival after diagnosis thresholds

  • June 24, 2026
New Korean health-screening data suggest prompt antidiabetic treatment after type 2 diabetes thresholds are crossed may improve survival,…
HHealth
New approach doubles chemotherapy effectiveness by targeting cancer cell memory
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Four OICR-funded studies explore transformative approaches in cancer care

  • May 14, 2026
Four new research studies funded by the Ontario Institute for Cancer Research (OICR) will deliver cutting-edge innovations by…
HHealth
Study: Survival and Recurrence With GLP-1 Receptor Agonists in Breast Cancer. Image Credit: zimmytws / Shutterstock
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Could GLP-1 drugs help breast cancer patients live longer?

  • May 13, 2026
A major real-world study links GLP-1 receptor agonists to improved survival and lower recurrence risk in women with…
SScience
New EASD guideline combines clinical standards with lived experience
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Metformin protects neurons after brain injury by restoring mitochondrial health

  • April 13, 2026
TBI remains a major cause of death and long-term neurological disability worldwide, yet effective treatments for secondary injury…
HHealth
Maldives achieves historic triple elimination of mother-to-child transmission of diseases
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Researchers explore “block and lock” strategy for functional HIV cure

  • March 23, 2026
For millions of people living with HIV, a daily regimen of medications is a lifelong necessity. If they…
HHealth
Blue background. White circular tablet. White texts says metformin which chemical structure drawn belowtext.
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A common diabetes drug may prevent long COVID when taken early

  • February 3, 2026
Large clinical trials and real-world data point to a familiar diabetes drug as a simple, safe way to…
HHealth
Cellular responses to ischemic reperfusion injury in young vs older donor organs. During ischemia, the deprivation of oxygen and nutrients leads to mitochondrial dysfunction and energy loss. In young cells, mitochondrial resilience helps sustain ATP production, ameliorating damage. Old cells, in contrast, experience significant ATP depletion, relying heavily on anaerobic metabolism, which leads to lactate buildup, pH reduction, and cellular stress. Upon reperfusion, the restoration of blood flow triggers oxidative stress as mitochondria generate excessive reactive oxygen species (ROS). Young cells compensate for those events through robust antioxidant systems, maintaining cellular integrity. Conversely, in old cells, impaired antioxidant defenses result in unregulated ROS production, furthermore damaging membranes, organelles, and DNA. Additionally, old cells release pro-inflammatory genes, amplifying local inflammation. Consequences are particularly severe in aged vascular endothelial cells, with ion pump dysfunction (e.g., Na⁺/K⁺ ATPase) causing ionic imbalances and cellular edema. This disruption exacerbates ischemic injury, progressing to irreversible damage. In contrast, young cells effectively resolve edema and inflammation through mechanisms that include macrophage945 mediated clearance of Damage-Associated Molecular Patterns (DAMPs) and anti-inflammatory cytokine release (e.g., IL-10 and TGF-β), allowing recovery and tissue repair. In old cells, persistent ROS generation, unresolved inflammation, and DAMP accumulation lead to irreversible inflammation, organelle collapse, and eventual cell death. Created in BioRender. Kayumov, M. (2025) https://BioRender.com/m23u7ro .
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Scientists outline how organ rejuvenation strategies could solve the donor shortage

  • December 12, 2025
New insights into cellular aging, perfusion technologies, and senescence-targeting treatments show how aging organs could be revived, turning…
HHealthcare
Yahoo news home
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Scientists Just Discovered a Surprising Side Effect of a Popular Diabetes Drug

  • November 23, 2025
Reviewed by Dietitian Emily Lachtrupp, M.S., RD Getty Images. EatingWell Design. Key Points Metformin may blunt blood vessel…
MMedication
Metformin
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Metformin, Meaning, Uses, Latest News

  • November 14, 2025
Metformin is an anti-diabetic medication (biguanide). Read more about Metformin, Meaning, Uses, Latest News. Metformin Latest News Metformin…
FFitness
Yahoo news home
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Scientists warn common diabetes drug may be cancelling out benefits of exercise

  • November 8, 2025
A widely prescribed diabetes drug may be blunting the beneficial effects of exercise in patients, a new study…
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