Scientists outline how organ rejuvenation strategies could solve the donor shortage
New insights into cellular aging, perfusion technologies, and senescence-targeting treatments show how aging organs could be revived, turning…
Nanoflower-treated stem cells deliver healthier mitochondria to stressed cells
By engineering nanomaterials that boost mitochondrial biogenesis, researchers show how stem cells can become powerful “mitochondrial biofactories,” offering…
Scientists recharge and repair human cells using donated mitochondria
Tiny structures inside your cells keep your body alive by turning food into fuel. These structures, called mitochondria,…
Scientists Find a Way to Help Aging Cells “Swap Their Batteries”
For decades, aging at the cellular level has been blamed on one tiny structure inside our cells: the…
Innate immunity and metabolic stress drive a unique form of cell death
In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study…
Free radicals generated at a specific site in astrocytes may promote dementia
Researchers have discovered that free radicals generated at a specific site in non-neuronal brain cells called astrocytes, may…
New gene-editing method can correct many disease-causing mutations in mammalian cells
Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person’s genome, often…
Exploring exercise’s physiological response to fight diabetes
Don’t love the gym? Neither does exercise scientist Ryan Montalvo. But he goes anyway. While any workout can…
Antidepressant fluoxetine alters brain energy use and boosts neural plasticity
A new study shows that the widely used antidepressant fluoxetine does more than boost serotonin levels: it…
Peroxisomes identified as alternative heat producers in brown fat
Researchers at Washington University School of Medicine in St. Louis have identified a novel way brown fat –…
New method reveals how mitochondrial DNA mutations influence cancer growth
Mitochondria act as energy factories in cells and have their own, separate DNA. Mutations to mitochondrial DNA (mtDNA)…
Rare ABCA7 gene variants linked to Alzheimer’s risk
A new study from MIT neuroscientists reveals how rare variants of a gene called ABCA7 may contribute to…