Stanford scientists make mouse skin transparent to study brain development
During childhood and adolescence, our brain goes through a lot of changes. But studying those changes in juvenile…
How a single gene reshapes pain perception through polyamine signaling
A breakthrough discovery reveals how the SLC45A4 gene fine-tunes polyamine transport in sensory neurons, reshaping our understanding of…
Computational approach provides insight into neural progenitor cells and their role in brain disorders
For much of the 20th century it was thought that the adult brain was incapable of regeneration. This…
Researchers gain better understanding of how nerve cells can be protected against ALS
By analyzing millions of messenger RNA molecules (mRNA) during the course of ALS, researchers at Stockholm University, in…
SNAP25 identified as key to sour taste perception and cell survival
The tongue contains numerous taste buds-tiny sensory organs responsible for detecting taste. Taste buds consist of specialized cells…
GIPR signaling opens brain’s gate for GLP-1 weight-loss therapy
A new study uncovers how GIPR signaling in brain cells helps GLP-1 weight-loss drugs bypass the blood-brain barrier…
Brain organoids reveal early changes in familial Alzheimer’s disease
Alzheimer’s disease (AD) is the most common neurodegenerative disease in older people, affecting up to 1 in 20…
Brain’s energy control map offers blueprint for next-gen weight loss therapies
A deep dive into the brain’s command center for hunger shows how decoding its circuits could transform the…
Special von Economo neurons may hold key to super-sharp memory in 80+ superagers
A 25-year study of ‘superagers’ reveals the brain and lifestyle factors that help some older adults defy typical…
Uncovering the secrets of ‘SuperAgers’ and cognitive longevity
For 25 years, scientists at Northwestern Medicine have been studying individuals aged 80 and older – dubbed “SuperAgers”…
Targeted microglia replacement shows promise against fatal neurodegenerative conditions
Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within…
Metformin’s blood sugar control starts in the brain, not just the liver, study finds
Scientists uncover how low-dose metformin targets brain pathways to lower blood sugar, opening fresh avenues for safer and…