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Browsing Tag

Preclinical

54 posts
HHealth
Study: Quality of life and safety of a dietary intervention with French maritime pine bark extract (Pycnogenol®) in women with osteoporotic bone loss: a randomized, placebo-controlled double-blind study - Part II. Image Credit: luchschenF / Shutterstock
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Women with low bone density reported less pain after taking pine bark extract

  • October 16, 2026
Could an extract from French maritime pine bark make everyday life easier for women with thinning bones? Researchers…
HHealth
brain made of fruits: Healthy food concept.
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Nutritionally similar meals might not affect your body the same way

  • October 8, 2026
Even with similar calories and nutrients, ultra-processed meals triggered stronger insulin responses and altered how the body burned…
HHealth
Experimental mRNA therapy protects the liver after acetaminophen overdose
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Experimental mRNA therapy protects the liver after acetaminophen overdose

  • September 29, 2026
When a patient arrives at the hospital with an acetaminophen overdose, it’s often a race against the clock.…
HHealth
Triple combination therapy trial for HR+/HER2− breast cancer halts early due to toxicity concerns
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Triple combination therapy trial for HR+/HER2− breast cancer halts early due to toxicity concerns

  • September 28, 2026
HR+/HER2− breast cancer constitutes approximately 65–75% of all breast cancer cases worldwide. Although CDK4/6 inhibitors have substantially extended progression-free survival (PFS), up…
TTechnology
Researchers find how prostate tumors reshape the immune microenvironment
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Researchers find how prostate tumors reshape the immune microenvironment

  • September 25, 2026
Researchers at The University of Texas MD Anderson Cancer Center have identified a previously unknown pathway that prostate…
HHealth
Review: GLP-1 Receptor Agonists, Gut Microbiota, and Chronic Pain: Nutritional Signaling at the Gut–Brain Axis
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GLP-1 drugs may influence chronic pain through gut-brain and immune pathways

  • September 24, 2026
From microbial metabolites and spinal microglia to osteoarthritis and headache trials, researchers map how GLP-1 signaling intersects with…
HHealth
Voluntary exercise reduces stress-linked bladder pain and urinary frequency
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Voluntary exercise reduces stress-linked bladder pain and urinary frequency

  • September 23, 2026
Chronic stress may contribute to the pain and urinary symptoms experienced by people with interstitial cystitis/bladder pain syndrome…
HHealth
Study: Ketogenic therapy as a potential novel treatment approach for PTSD: an integrative review and proposed mechanistic model. Image Credit: Cat Box / Shutterstock
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Early studies hint that ketones may affect pathways linked to PTSD

  • September 11, 2026
From altered brain energy metabolism to inflammation and neurotransmitter signaling, researchers examine why raising ketone levels has drawn…
HHealth
Review: Diet–gut microbiota–immune–brain interactions in aging: mechanistic pathways and clinical implications. Image Credit: Toey Andante / Shutterstock
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What your gut microbes may have to do with how your brain ages

  • September 4, 2026
From microbial metabolites and intestinal barriers to immune signaling and the brain, researchers map the complex biological pathways…
SScience
Biodegradable 'nanobone' material helps body regrow jawbone
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Biodegradable ‘nanobone’ material helps body regrow jawbone

  • September 3, 2026
For children born with cleft lip and palate, repairing gaps in the jawbone often means waiting until they…
HHealth
Targeting KV7 proteins could help delay preterm labor
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Targeting KV7 proteins could help delay preterm labor

  • September 3, 2026
Scientists have found that targeting a particular group of proteins in the uterus muscle (myometrium) can suppress human…
HHealth
Study identifies a promising new strategy for treating alcohol use disorder
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Loneliness can reprogram the brain to increase alcohol use

  • August 25, 2026
Loneliness can reprogram the brain in ways that push alcohol consumption, reports a new preclinical study led by…
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