New molecular signatures map the stepwise development of gastric cancer
Gastric cancer often develops through a gradual sequence of changes, beginning with superficial gastritis and advancing through chronic…
Differential cold stress intensities drive unique morphological and transcriptomic changes in Zea mays root hairs | BMC Genomics
Kennett DJ, Prufer KM, Culleton BJ, George RJ, Robinson M, et al. Early isotopic evidence for maize as…
MSnLib: efficient generation of open multi-stage fragmentation mass spectral libraries
Materials All solvents used were of LC–MS grade. Methanol, acetonitrile, water and formic acid were obtained from Thermo…
Investigating the role of transposable elements in shaping abdominal fat and egg production phenotypic traits in geese | BMC Genomics
Shi X, Wang J, Zeng F, Qiu X. Mitochondrial DNA cleavage patterns distinguish independent origin of Chinese domestic…
Gut disorders forecast Alzheimer’s and Parkinson’s risk years before diagnosis
Common, treatable gut-related conditions signal Alzheimer’s and Parkinson’s disease risk long before symptoms, paving the way for earlier,…
Imaging-based multimodal profiling of single cells with STAMP
Single-cell RNA sequencing (scRNA-seq) has dramatically advanced our ability to dissect complex biological systems at cellular resolution. However,…
New strategies to tackle resistant foodborne pathogens
Researchers show how advanced sequencing and natural compounds are shaping the ongoing fight against deadly foodborne diseases, from…
Alzheimer’s research reaches a critical tipping point
One-third of people older than 85 in the United States are estimated to live with Alzheimer’s disease today,…
Morphological map of under- and overexpression of genes in human cells
Mattiazzi Usaj, M. et al. High-content screening for quantitative cell biology. Trends Cell Biol. 26, 598–611 (2016). CAS …
Genetic markers could help prevent age-related frailty
New research links previously unknown genes to frailty, raising hope for early predicting and preventing age-related decline. Study:Â Large-scale…
New insights into how genes influence frailty in older adults
A new study has identified genetic variants linked to brain function, immune defense and metabolism that contribute to…
The Platinum Pedigree: a long-read benchmark for genetic variants
Gonzaga-Jauregui, C., Lupski, J. R. & Gibbs, R. A. Human genome sequencing in health and disease. Annu. Rev.…