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Browsing Tag

Receptor

110 posts
HHealth
Study: Advancing child health: forecasting the next great research achievements. Image Credit: New Africa / Shutterstock
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Pediatric experts reveal the 10 research areas set to shape child health

  • June 2, 2026
From gene therapy and AI to vaccines, nutrition, and cancer care, pediatric research leaders outline where the next…
HHealth
Study: Survival and Recurrence With GLP-1 Receptor Agonists in Breast Cancer. Image Credit: zimmytws / Shutterstock
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Could GLP-1 drugs help breast cancer patients live longer?

  • May 13, 2026
A major real-world study links GLP-1 receptor agonists to improved survival and lower recurrence risk in women with…
HHealth
New EASD guideline combines clinical standards with lived experience
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Diabetes, weight-loss drugs not a perfect fit?

  • May 11, 2026
Type 2 diabetes affects millions of people worldwide and now a new international study, jointly led by Adelaide…
HHealth
Exercise or caffeine? Study finds neither clearly beats placebo for mental fatigue
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Exercise or caffeine? Study finds neither clearly beats placebo for mental fatigue

  • May 11, 2026
A 20-minute cycling session raised heart rate, and caffeine raised physiological arousal, but neither clearly protected young adults…
HHealth
Study finds surge in the use of weight loss drugs among bariatric surgery patients
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GLP-1 drugs combined with surgery yield superior weight loss results

  • May 5, 2026
People who begin obesity treatment with glucagon-like peptide-1 receptor agonists (GLP-1s) and then undergo metabolic and bariatric surgery…
HHealth
Study: Postprandial lipid metabolism durably enhances T cell immunity. Image Credit: Vink Fan / Shutterstock
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Food timing may shape how T cells respond to infection and therapy

  • May 1, 2026
A new study reveals how lipids released after a meal can durably boost T cell metabolism, translation, and…
HHealth
A doctor performs a breast examination on a female patient in a medical setting.
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How cost, access, and awareness barriers are slowing BRCA testing

  • April 29, 2026
Despite broader guidelines and life-saving targeted therapies, real-world evidence reveals persistent gaps and inequities in BRCA testing, raising…
HHealth
GLP-1 receptor agonists: The good, the bad, and the ugly - A comprehensive guide for NPs. Image Credit: zimmytws / Shutterstock
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GLP-1 drugs promise wider health benefits, but experts urge caution on use

  • April 28, 2026
As GLP-1 receptor agonists move beyond blood sugar and weight loss, a new review shows why clinicians must…
SScience
Targeting glutamine metabolism enhances CAR-macrophage cancer therapy
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Targeting glutamine metabolism enhances CAR-macrophage cancer therapy

  • April 21, 2026
Tumor-associated macrophages (TAMs) within the tumor microenvironment (TME) exhibit significant metabolic dysregulation, which impairs their antitumor function. Specifically,…
HHealth
Innate immune activation and microglial transition during neurodegeneration. (A) During neurodegeneration, distressed neurons release DAMPs such as mtDNA, ROS, HMGB1, aberrant proteins, and pTau–bound RNA. These signals activate resident microglia and astrocytes, which then recruit peripheral immune cells. As shown in more detail in B, activated microglia upregulate PRRs, including TLRs, RAGE, and cGAS, enabling detection of neuron-derived DAMPs. Engagement of PRRs induces proinflammatory gene expression programs and activates inflammasome pathways that promote release of chemokines and cytokines into the CNS parenchyma. As microglia transition from homeostatic to reactive states in a TREM2-dependent manner, damage-associated microglia increase MHC-II expression to support antigen presentation and coordination of adaptive immune responses that attempt to limit neurodegeneration.
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How the immune system may influence Alzheimer’s, Parkinson’s, and related diseases

  • April 17, 2026
A sweeping review shows how the brain’s immune defenses can both fight and fuel neurodegeneration, revealing why timing,…
HHealth
Excessive amounts of visceral fat tied to faster heart aging
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Bayer receives MHRA approval for Kerendia® (finerenone) in adults with heart failure with LVEF ≥ 40 %

  • April 13, 2026
The Medicines and Healthcare products Regulatory Agency (MHRA) has granted approval for Kerendia® (finerenone), a non-steroidal, selective mineralocorticoid…
SScience
Insights into the clinical presentation and management of sellar chondrosarcomas
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Molecular switch in neurons found to limit the regrowth of damaged axonal fibers

  • April 1, 2026
Researchers from the Icahn School of Medicine at Mount Sinai have discovered a molecular switch in neurons that…
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