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Browsing Tag

stress

234 posts
MMental health
'AGT' judge Howie Mandel on OCD: 'I'm in this nightmare'
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‘AGT’ judge Howie Mandel on OCD: ‘I’m in this nightmare’

  • December 15, 2025
Howie Mandel talks ‘AGT’ sexiness, live-show vibe from makeup chair During a pre-show makeup session in his dressing…
HHealth
A new trial investigates whether the MIND diet can be scaled for obesity management
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A new trial investigates whether the MIND diet can be scaled for obesity management

  • December 15, 2025
Researchers in Sweden are testing whether a brain-healthy MIND diet can be realistically adopted by adults with obesity,…
MMental health
YourTango
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10 Smart Ways People Handled Stress In The 1970s That Modern Generations Won’t Even Try

  • December 14, 2025
While the idea of “wellness” today has been misconstrued with consumerism and immediate gratification, the true roots of…
HHealth
Etomidate proves safer than ketamine for emergency intubations
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Etomidate proves safer than ketamine for emergency intubations

  • December 13, 2025
Doctors treating seriously ill patients in an emergency setting may want to give the sedative etomidate, rather than ketamine,…
SScience
Study: Acute Impact of Polyphenol-Rich vs. Carbohydrate-Rich Foods and Beverages on Exercise-Induced ROS and FRAP in Healthy Sedentary Female Adults - A Randomized Controlled Trial. Image Credit: Improvisor / Shutterstock
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How specific foods reshape oxidative stress responses during and after high-intensity training

  • December 12, 2025
A new randomized trial reveals how simple food choices before and after fasted HIIT can shift the body’s…
HHealth
Cellular responses to ischemic reperfusion injury in young vs older donor organs. During ischemia, the deprivation of oxygen and nutrients leads to mitochondrial dysfunction and energy loss. In young cells, mitochondrial resilience helps sustain ATP production, ameliorating damage. Old cells, in contrast, experience significant ATP depletion, relying heavily on anaerobic metabolism, which leads to lactate buildup, pH reduction, and cellular stress. Upon reperfusion, the restoration of blood flow triggers oxidative stress as mitochondria generate excessive reactive oxygen species (ROS). Young cells compensate for those events through robust antioxidant systems, maintaining cellular integrity. Conversely, in old cells, impaired antioxidant defenses result in unregulated ROS production, furthermore damaging membranes, organelles, and DNA. Additionally, old cells release pro-inflammatory genes, amplifying local inflammation. Consequences are particularly severe in aged vascular endothelial cells, with ion pump dysfunction (e.g., Na⁺/K⁺ ATPase) causing ionic imbalances and cellular edema. This disruption exacerbates ischemic injury, progressing to irreversible damage. In contrast, young cells effectively resolve edema and inflammation through mechanisms that include macrophage945 mediated clearance of Damage-Associated Molecular Patterns (DAMPs) and anti-inflammatory cytokine release (e.g., IL-10 and TGF-β), allowing recovery and tissue repair. In old cells, persistent ROS generation, unresolved inflammation, and DAMP accumulation lead to irreversible inflammation, organelle collapse, and eventual cell death. Created in BioRender. Kayumov, M. (2025) https://BioRender.com/m23u7ro .
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Scientists outline how organ rejuvenation strategies could solve the donor shortage

  • December 12, 2025
New insights into cellular aging, perfusion technologies, and senescence-targeting treatments show how aging organs could be revived, turning…
SScience
Beta blockers reduce mortality and heart failure in MI patients with mildly reduced ejection fraction
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Collaborative project seeks safer therapies for ischemia and reperfusion injury

  • December 11, 2025
Southwest Research Institute (SwRI) and Trinity University will improve a prodrug, a compound activated in the body, to…
SScience
Study: Nanomaterial-induced mitochondrial biogenesis enhances intercellular mitochondrial transfer efficiency. Image Credit: Julien Tromeur / Shutterstock
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Nanoflower-treated stem cells deliver healthier mitochondria to stressed cells

  • December 10, 2025
By engineering nanomaterials that boost mitochondrial biogenesis, researchers show how stem cells can become powerful “mitochondrial biofactories,” offering…
MMental health
Medical Mysteries: For years she was told it was stress – a brain scan revealed the real cause
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Medical Mysteries: For years she was told it was stress – a brain scan revealed the real cause

  • December 8, 2025
“It was concerning for me,” she said. “I’d always been regular, never on birth control.” Her gynaecologist suggested…
HHealth
Innovative VR therapy helps ease anxiety in cardiovascular disease
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Psychosocial stress in women linked to early signs of heart tissue changes

  • December 5, 2025
Women who report high levels of psychosocial stress, such as from caregiving and lack of emotional support, show…
HHealth
Better sleep quality and healthy habits linked to improved mental wellbeing in young adults
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Rising nighttime heat is linked to shorter and more disrupted sleep

  • December 5, 2025
Higher nighttime temperatures are linked to shorter sleep times and lower sleep quality, especially for people with chronic…
HHealth
Middle precentral gyrus plays key role in orchestrating speech movements
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Understanding how adult brains adapt to challenge and change

  • December 4, 2025
In a revelatory Genomic Press Interview published today in Brain Medicine, Dr. Paul Lucassen, full professor at the…
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