Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…
Thiostrepton suppresses rhabdomyosarcoma progression by targeting the PI3K–AKT pathway
Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.…
Researchers develop a new approach for treating children with neuroblastoma
A research team from the University of Zurich and the University Children’s Hospital Zurich has developed a new…
CRATERs identified as key sites for T cell-mediated tumor destruction
Like the surface of the moon, new research published today in Cell finds the existence of craters on…
Cleveland Clinic team uncovers genetic link to osteosarcoma
Researchers at Cleveland Clinic Children’s have helped identify a previously unknown gene that increases the risk of developing…
Innovative system accurately detects genetic mutations in the brain tumor within 25 minutes
A research team in Japan has developed an innovative system that can accurately detect genetic mutations in the…
Next-generation imaging promises sharper, deeper view of living tissues
A University of Arizona research team will receive nearly $2.7 million from the NIH’s Common Fund Venture Program to advance next-generation…
Deadly brain cancer erodes skull bone and alters immune marrow
Scientists at Montefiore Einstein Comprehensive Cancer Center (MECCC) and Albert Einstein College of Medicine have shown for the…
Radiomics significantly outperforms clinical models for predicting NPC treatment outcome
Nasopharyngeal carcinoma (NPC) is a highly aggressive malignancy, with most patients presenting at locally advanced stages. While immune…
Genetic testing guides personalized radiation patients with HPV-positive throat cancer
Genetic testing can identify patients with HPV-positive throat cancer who may benefit from lower radiation doses, according to…
Greek yogurt after exercise lowers inflammation more than carbs
Researchers discovered that young men who ate Greek yogurt after training showed lower levels of inflammation than those…
Understanding how lipids activate LC3-associated phagocytosis
LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles. It plays a…