The Week 1 college football schedule brings dozens of intriguing matchups that will shape the early College Football Playoff picture. Games run from Thursday through Monday, highlighted by three ranked matchups involving top-10 teams with Texas vs. Ohio State (-1.5), LSU vs. Clemson (-3.5) and Notre Dame vs. Miami (+2.5). Those college football spreads are all within a touchdown, but there are also some giants numbers on the Week 1 college football odds board as some teams are starting out with easier opponents.<\/p>\n
Indiana is a 23.5-point favorite over Old Dominion, per the Week 1 college football spreads, while Texas A&M is favored by 23.5 points over UTSA. Those are among a handful of games with Week 1 college football spreads of at least 20 points. Making college football predictions for season openers are always a bit difficult given the amount of player movement there is, and there’s no in-season data to go by. Before locking in any Week 1 college football picks, be sure to see the latest Week 1 college football predictions from SportsLine’s proven model<\/a>.<\/p>\n The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and was a profitable 27-16 combined on money-line and over\/under\u00a0college football picks<\/a>\u00a0in 2024. Anybody following its\u00a0college football betting<\/a>\u00a0picks at\u00a0sportsbooks<\/a>\u00a0and on\u00a0betting sites<\/a>\u00a0could have seen strong returns.<\/p>\n Now, it has turned its attention to the latest college football odds<\/a>\u00a0and Week 1 college football betting<\/a> lines on the spread, money line, and over\/under.\u00a0Head here to see every pick<\/a>, and new users can also target the\u00a0DraftKings promo code<\/a>, which offers new users\u00a0$300 in bonus bets instantly plus over $200 off NFL Sunday Ticket<\/a>:<\/p>\n Top college football predictions for Week 1\u00a0<\/p>\n One of the college football picks the model is high on during Week 1: No. 8 Alabama<\/a> (-13.5) cruises to a blowout win over Florida State<\/a> at 3:30 p.m. ET on Saturday. The Tide are riding a 23-game win streak in season openers which is the second-longest active streak in the country. They are also an astounding 63-1 in regular season non-conference games since 2008, with Kalen DeBoer winning by an average of 48 points in his three such contests in his first year at Bama. As for the Seminoles, they are coming off a 2-10 record that was their worst in 50 years.<\/p>\n FSU simply struggled to move the ball in 2024, ranking third-worst in all of FBS in total offense and fourth-worst in scoring offense. That’s a bad omen in facing a Bama team which had a top-10 scoring defense in the country last year. Florida State covered in just three games all of last season, and it is 1-6 against the spread over its last seven versus top-10 ranked SEC schools. The model projects Alabama to win by over two touchdowns and cover nearly 60% of the time.\u00a0See which other picks the model likes here<\/a>.<\/p>\n Another prediction: UCLA<\/a> (+5.5) stays within the spread at home versus Utah<\/a> at 11 p.m. ET on Saturday. These former Pac-12 rivals last met in the Rose Bowl Stadium in 2022 in which the Bruins protected home turf with a 10-point win. UCLA had a strong finish last season, going 4-2 down the stretch and then landed arguably the biggest of quarterback transfers in former Tennessee star Nico Iamaleava. Just as the Bruins finished 2024 on a high note, so did Iamaleava with the Vols as he had 13 total touchdowns versus just one interception over his last six games of 2024.<\/p>\n Meanwhile, Utah is coming off its first losing season (5-7) since 2013 and is breaking in a quarterback, Devon Dampier, who had as many interceptions (12) as touchdown passes a year ago. The New Mexico transfer is 0-2 in his career versus Power 4 programs, with two interceptions thrown in each game. UCLA covers well over 60% of the time, per the model, with the Under (51.5) hitting in 80% of simulations.\u00a0See the rest of the model’s picks here<\/a>.<\/p>\n How to make college football picks for Week 1<\/p>\n The model has also made the call on who wins and covers in every FBS matchup in Week 1, and it’s calling for an upset in one of the week’s biggest games.\u00a0You can only get every pick for every game at SportsLine<\/a>, and for a limited time you can use promo code CHAMPIONSHIP to get your first month at SportsLine for $1.<\/p>\n So what college football picks can you make with confidence, and which underdog wins outright? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $2,000 in profit since its inception<\/a>, and find out.<\/p>\n Week 1 college football odds for notable games<\/p>\n See full Week 1 college football picks, odds, predictions here<\/a><\/p>\n (odds subject to change)<\/p>\n Thursday, Aug. 28<\/p>\n Boise State<\/a> vs. South Florida<\/a> (+5.5, 62.5)<\/p>\n Ohio vs. Rutgers (-15.5, 51.5)<\/p>\n Miami (OH) vs. Wisconsin (-17.5, 40.5)<\/p>\n Nebraska vs. Cincinnati (+6.5, 51.5)<\/p>\n Friday, Aug. 29<\/p>\n Kennesaw State vs. Wake Forest (-17.5, 51.5)<\/p>\n Auburn vs. Baylor (+2.5, 58.5)<\/p>\n Saturday, Aug. 30<\/p>\n Texas vs. Ohio State (-1.5, 47.5)<\/p>\n Tennessee vs. Syracuse<\/a> (+13.5, 50.5)<\/p>\n Indiana<\/a> vs. Old Dominion<\/a> (+22.5, 54.5)<\/p>\n Alabama vs. Florida State (+13.5, 50.5)<\/p>\n Georgia vs. Marshall (+39.5, 55.5)<\/p>\n Penn State vs. Nevada (+44.5, 57.5)<\/p>\n Texas A&M<\/a> vs. UTSA<\/a> (-22.5, 56.5)<\/p>\n Clemson vs. LSU (+3.5, 57.5)<\/p>\n Michigan<\/a> vs. New Mexico State<\/a> (+36.5, 50.5)<\/p>\n Ole Miss<\/a> vs. Georgia State<\/a> (+38, 61.5)<\/p>\n UTEP vs. Utah State (-6, 60.5)<\/p>\n Utah vs. UCLA (+6, 50.5)<\/p>\n Sunday, Aug. 31<\/p>\n South Carolina<\/a> vs. Virginia Tech<\/a> (+7.5, 50.5)<\/p>\n Notre Dame vs. Miami (+2.5, 49.5)<\/p>\n Monday, Sept. 1<\/p>\n TCU<\/a> vs. North Carolina<\/a> (+3, 58.5)<\/p>\n","protected":false},"excerpt":{"rendered":"The Week 1 college football schedule brings dozens of intriguing matchups that will shape the early College Football…\n","protected":false},"author":2,"featured_media":102818,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[563],"tags":[1214,64,63,594,1216,596,85,1415,1230],"class_list":["post-102817","post","type-post","status-publish","format-standard","has-post-thumbnail","category-football","tag-alabama-crimson-tide","tag-au","tag-australia","tag-college-football","tag-florida-state-seminoles","tag-football","tag-sports","tag-ucla-bruins","tag-utah-utes"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/102817","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/comments?post=102817"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/102817\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media\/102818"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media?parent=102817"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/categories?post=102817"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/tags?post=102817"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}